Skip Header

Contribute Send feedback
Read comments (?) or add your own

B1MD52 (B1MD52_MYCA9) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Dihydrodipicolinate reductase HAMAP MF_00102
Short name=DHPR HAMAP MF_00102
EC=1.3.1.26 HAMAP MF_00102
Gene names
Name:dapB HAMAP MF_00102
Ordered Locus Names:MAB_3096c
OrganismMycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]
Taxonomic identifier561007 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length245 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)+ = (S)-2,3-dihydrodipicolinate + NAD(P)H. HAMAP MF_00102 SAAS SAAS022664

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4. HAMAP MF_00102 SAAS SAAS022664

Subcellular location

Cytoplasm By similarity HAMAP MF_00102 SAAS SAAS022664.

Sequence similarities

Belongs to the dihydrodipicolinate reductase family. HAMAP MF_00102

Sequences

Sequence LengthMass (Da)Tools
B1MD52 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 8FCD166CB07CBA62

FASTA24525,604
        10         20         30         40         50         60 
MTNIATGVLG AQGKVGQAMC QAVDSAADLD LVAAVDKNDS LEALTAASVV IDFTHPDVVM 

        70         80         90        100        110        120 
DNLKFLIGKG IHAVVGTTGF TDERLDQVRS WLADSPGTGV LIAPNFAIGA VLSMKFAQQA 

       130        140        150        160        170        180 
ARFFESVEII ELHHPNKADA PSGTATRTAR LIAEARRGLP PSPDATSTGL EGARGADVDG 

       190        200        210        220        230        240 
VRVHAVRVSG LVAHQEVLFG TTGETLTIRH DSIDRSSFAP GVLLAVRDIA KRPGLTIGIE 


PLLEL

« Hide

References

[1]"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus."
Genoscope
Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU458896 Genomic DNA. Translation: CAM63173.1.
RefSeqYP_001703827.1. NC_010397.1.

3D structure databases

ProteinModelPortalB1MD52.
SMRB1MD52. Positions 7-245.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1MD52.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000008703; EBMYCP00000008642; EBMYCG00000008701.
GeneID5965602.
GenomeReviewsGene locus MAB_3096c in contig CU458896_GR.
KEGGmab:MAB_3096c.
PATRIC17977948. VBIMycAbs55940_3147.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000017074.
HOGENOMHBG594002.
OMADRASFMP.

Family and domain databases

HAMAPMF_00102. DapB.
[Tree]
InterProIPR022663. DapB_C.
IPR000846. DapB_N.
IPR022664. DapB_N_CS.
IPR011770. Dihydrodipicolinate_Rdtase.
IPR023940. Dihydrodipicolinate_Rdtase_bac.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00215.
PANTHERPTHR20836. DapB_bac/pln. 1 hit.
PfamPF05173. DapB_C. 1 hit.
PF01113. DapB_N. 1 hit.
[Graphical view]
PIRSFPIRSF000161. DHPR. 1 hit.
TIGRFAMsTIGR00036. DapB. 1 hit.
PROSITEPS01298. DAPB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1MD52_MYCA9
AccessionPrimary (citable) accession number: B1MD52
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info