B1MC30 (B1MC30_MYCA9) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Enoyl-[acyl-carrier-protein] reductase [NADH] PIRNR PIRNR000094
EC=1.3.1.9 PIRNR PIRNR000094

Gene names

Ordered Locus Names:

MAB_2722c

Organism

Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]

Taxonomic identifier

561007 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length	269 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acyl-[acyl-carrier-protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH. PIRNR PIRNR000094
Pathway	Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094

Ontologies

Keywords
Biological process	Fatty acid biosynthesis PIRNR PIRNR000094 Lipid synthesis
Ligand	NAD PIRNR PIRNR000094
Molecular function	Oxidoreductase PIRNR PIRNR000094
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	enoyl-[acyl-carrier-protein] reductase (NADH) activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	158	1	Proton acceptor By similarity PIRSR PIRSR000094-1

Sequences

	Sequence		Length	Mass (Da)
	B1MC30 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 5DD5DDF14BC2CDB3	FASTA	269	28,636
	10 20 30 40 50 60 MAGLLEGKRI LVTGIITDSS IAFHIAKVAQ EQGAELVLTG FDRLRLIERI TQRLPKPAPL 70 80 90 100 110 120 LELDVQNEEH LGSLAGRISE VIGEGNKLDG VVHSIGFMPQ SGMGVNPFFD APFADVSKGF 130 140 150 160 170 180 HISAFSYSSL AKAVLPVMNR GGSIVGMDFD PTRAMPAYNW MTVAKSALES VNRFVAREAG 190 200 210 220 230 240 KVGVRSNLVA AGPIRTLAMS AIVGGALGDE AGQQMQLLEE GWDQRAPIGW DMKDPTPVAK 250 260 TVCALLSDWL PATTGDIIFA DGGAHTQLL

References

[1]

"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus." Genoscope Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU458896 Genomic DNA. Translation: CAM62801.1.
RefSeq	YP_001703455.1. NC_010397.1.
3D structure databases
ProteinModelPortal	B1MC30.
SMR	B1MC30. Positions 2-269.
ModBase	Search...
Protein-protein interaction databases
STRING	B1MC30.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000008450; EBMYCP00000008389; EBMYCG00000008448.
GeneID	5965230.
GenomeReviews	Gene locus MAB_2722c in contig CU458896_GR.
KEGG	mab:MAB_2722c.
PATRIC	17977178. VBIMycAbs55940_2766.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000015205.
HOGENOM	HBG750976.
ProtClustDB	PRK07889.
Family and domain databases
InterPro	IPR014358. Enoyl-ACP_Rdtase_NADH. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K11611.
PIRSF	PIRSF000094. Enoyl-ACP_rdct. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1MC30_MYCA9

Accession

Primary (citable) accession number: B1MC30

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)