B1MC05 (B1MC05_MYCA9) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA polymerase III alpha subunit EMBL CAM62776.1

Gene names

Ordered Locus Names:

MAB_2696c

Organism

Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]

Taxonomic identifier

561007 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length	1185 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). SAAS SAAS004013

Ontologies

Keywords
Biological process	DNA replication SAAS SAAS004013
Cellular component	Cytoplasm SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1MC05 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: F7BA8786572FA501	FASTA	1,185	129,483
	10 20 30 40 50 60 MSSSNSSFVH LHNHTEYSML DGAAKIKPML AEVERLGMSA VGMTDHGNMY GASEFYNVAA 70 80 90 100 110 120 ATGVKPIIGI EAYIAPASRF DTKRVFWGDP GQKSDDVSGS GSYTHMTMVA ENATGLRNLF 130 140 150 160 170 180 KLSSLASFEG QLGKWARMDA DLIAEHASGI IATTGCPSGE VQTRLRLGQE SEALAAAAKW 190 200 210 220 230 240 QDIFGKDNFF LELMDHGLSI ERRVREGLLE VGKKLGIPPL ATNDCHYVTK DHAHNHEALL 250 260 270 280 290 300 CVQTGKTLSD PTRFKFDGDG YYLKPASEMR DLWDDAVPGA CDNTLLIAER VQSYEDVWNF 310 320 330 340 350 360 KDRMPIFPVP EGEDQDSWLR KEVDRGLERR FEGVPGGVPD EYFTRAHYEL DVIKQKGFPA 370 380 390 400 410 420 YFLVVGDLVS HAKEVGIRVG PGRGSAAGSL VAYALGITNI DPIPHGLLFE RFLNPERPSA 430 440 450 460 470 480 PDIDIDFDDR RRGEMVRYAT EKWGSDRVAQ VITFGTIKTK AALKDSARIH YGQPGFAIAD 490 500 510 520 530 540 RITKALPPPI MAKDIPVWGI TNPEHERYKE AAEVRTLIDT DPDVRNIYQT ALGLEGLIRN 550 560 570 580 590 600 AGVHACAVIM SSEPLTDAIP LWKRAQDGAI ITGWDYPSCE AIGLLKMDFL GLRNLTVIGD 610 620 630 640 650 660 ALDNIKANRG IDLDLDHLPL DDPATYELLS RGDTLGVFQL DGGPMRDLLR RMQPTGFNDI 670 680 690 700 710 720 VAVLALYRPG PMGMNAHNDY ADRKNGRQPI KPIHPELEEP LKDILAETFG LIVYQEQIMF 730 740 750 760 770 780 IAQKVASYSM GKADALRKAM GKKKLEVLEA EYKGFYEGMT NNGFSEKAVK ALWDTILPFA 790 800 810 820 830 840 GYAFNKSHAA GYGLVSFWTA YLKANYPAEY MAGLLTSVGD DKDKAAVYLA DCRRLGITVL 850 860 870 880 890 900 PPDVNESVHN FASVGEDIRY GLGGVRNVGA NVVQSLIATR EEKGAFTDFS DYLHKIDIAA 910 920 930 940 950 960 CNKKVTESLV KAGAFDSLGH PRKGLFLVQS DAVDSVLGTK KAEAMGQFDL FGGGGEDSVP 970 980 990 1000 1010 1020 ASDIFAIKVP DDEWEEKHKL ALEREMLGLY VSGHPLNGVA HLLSRQTDTQ IPAILDGEVA 1030 1040 1050 1060 1070 1080 NDAVVKVGGI LASVNRRVNK NGMPWASAQL EDLTGGIEVL FFPQAYSVYG ADIADDAVVL 1090 1100 1110 1120 1130 1140 VNAKVAIRDD RVSLIANDLV VPDFSQAADD RPVAVTMPTR QCTIDKVTAL KQVLTRHPGT 1150 1160 1170 1180 NQVHLRLISG ERVTTLELDQ SLRVTPSSAL MGDLKALLGP GCLGG

References

[1]

"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus." Genoscope Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU458896 Genomic DNA. Translation: CAM62776.1.
RefSeq	YP_001703430.1. NC_010397.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B1MC05.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000007719; EBMYCP00000007658; EBMYCG00000007717.
GeneID	5965205.
GenomeReviews	Gene locus MAB_2696c in contig CU458896_GR.
KEGG	mab:MAB_2696c.
PATRIC	17977126. VBIMycAbs55940_2740.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000016568.
HOGENOM	HBG734490.
OMA	RVLQMPY.
ProtClustDB	PRK05673.
Family and domain databases
InterPro	IPR011708. DNA_pol3_alpha. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K02337.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1MC05_MYCA9

Accession

Primary (citable) accession number: B1MC05

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)