Cytidylate kinase - Mycobacterium abscessus (strain ATCC 19977 / DSM 44196)

Contribute

Read comments (?) or add your own

B1MB31 (B1MB31_MYCA9) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 28. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

text xml rdf/xml gff fasta

to top of page

Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

to top of page

Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Recommended name:
Cytidylate kinase HAMAP MF_00238
Short name=CK HAMAP MF_00238
EC=2.7.4.25 HAMAP MF_00238

Alternative name(s):
Cytidine monophosphate kinase HAMAP MF_00238

Gene names

Name:	cmk HAMAP MF_00238
Ordered Locus Names:	MAB_2371

Organism

Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]

Taxonomic identifier

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length	223 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238 SAAS SAAS011994
Subcellular location	Cytoplasm By similarity HAMAP MF_00238.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily. HAMAP MF_00238

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00238
Ligand	ATP-binding HAMAP MF_00238 SAAS SAAS011994 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00238 SAAS SAAS011994 EMBL CAM62452.1 Transferase
Technical term	3D-structure PDB 3R8C Complete proteome
Gene Ontology (GO)
Biological process	pyrimidine nucleotide metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP cytidylate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

B1MB31 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 2DD174907CDB149C
Show »

223

23,443

        10         20         30         40         50         60 
MVAVDGPSGT GKSSVAKELA RQLGASYLDT GAMYRIVTLW VLRAGVDLTD PAAIAAATDQ 

        70         80         90        100        110        120 
VPMSVSSDPD AQTALLAGED VSVPIRGNEV TGAVSAVSAV PAVRERLVRQ QRELAESSGA 

       130        140        150        160        170        180 
VVVEGRDIGT VVLPDADVKI YLTASAQARA QRRNAQNVSG GGDDEYEKVL ADVQRRDHLD 

       190        200        210        220 
STRAVSPLRP AEDALEVDTS DMTQEQVVAH LLDLVRTRAG ASR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus." Genoscope Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Crystal structure of cytidylate kinase (Cmk) from Mycobacterium abscessus." Seattle Structural Genomics Center for Infectious Disease (SSGCID) Edwards T.E., Clifton M.C. Submitted (MAR-2011) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 2-223.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CU458896 Genomic DNA. Translation: CAM62452.1.

RefSeq

YP_001703106.1. NC_010397.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3R8C	X-ray	2.20	A/B	2-223	[»]

ProteinModelPortal

ModBase

Protein-protein interaction databases

STRING

Protocols and materials databases

StructuralBiologyKnowledgebase

Genome annotation databases

EnsemblBacteria

EBMYCT00000005593; EBMYCP00000005532; EBMYCG00000005591.

GeneID

GenomeReviews

Gene locus MAB_2371 in contig CU458896_GR.

KEGG

PATRIC

17976472. VBIMycAbs55940_2414.

Organism-specific databases

CMR

Phylogenomic databases

GeneTree

EBGT00050000015811.

HOGENOM

OMA

Family and domain databases

HAMAP

MF_00238. Cytidyl_kinase_type1.
[Tree]

InterPro

IPR003136. Cytidylate_kin.
IPR011994. Cytidylate_kinase_dom.
[Graphical view]

KO

PANTHER

PTHR21299:SF2. Cytidylate_kin. 1 hit.

Pfam

PF02224. Cytidylate_kin. 1 hit.
[Graphical view]

TIGRFAMs

TIGR00017. Cmk. 1 hit.

ProtoNet

Entry information

Entry name

B1MB31_MYCA9

Accession

Primary (citable) accession number: B1MB31

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

to top of page

Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info