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Protein

Cytidylate kinase

Gene

cmk

Organism
Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + (d)CMP = ADP + (d)CDP.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi6 – 149ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationImported, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMABS36809-WGS:GSQO-2384-MONOMER.
MABS561007:GJTG-2384-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytidylate kinaseUniRule annotationSAAS annotation (EC:2.7.4.25UniRule annotationSAAS annotation)
Short name:
CKUniRule annotation
Alternative name(s):
Cytidine monophosphate kinaseUniRule annotation
Gene namesi
Name:cmkUniRule annotation
Ordered Locus Names:MAB_2371Imported
OrganismiMycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)Imported
Taxonomic identifieri561007 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium abscessus
Proteomesi
  • UP000007137 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi561007.MAB_2371.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3R8CX-ray2.20A/B2-223[»]
4DIEX-ray2.65A/B/C/D2-223[»]
ProteinModelPortaliB1MB31.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 216215Cytidylate_kinInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the cytidylate kinase family. Type 1 subfamily.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CAT. Bacteria.
COG0283. LUCA.
HOGENOMiHOG000242850.
OMAiVRARRRY.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00238. Cytidyl_kinase_type1. 1 hit.
InterProiIPR003136. Cytidylate_kin.
IPR011994. Cytidylate_kinase_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF02224. Cytidylate_kin. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00017. cmk. 1 hit.

Sequencei

Sequence statusi: Complete.

B1MB31-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVAVDGPSGT GKSSVAKELA RQLGASYLDT GAMYRIVTLW VLRAGVDLTD
60 70 80 90 100
PAAIAAATDQ VPMSVSSDPD AQTALLAGED VSVPIRGNEV TGAVSAVSAV
110 120 130 140 150
PAVRERLVRQ QRELAESSGA VVVEGRDIGT VVLPDADVKI YLTASAQARA
160 170 180 190 200
QRRNAQNVSG GGDDEYEKVL ADVQRRDHLD STRAVSPLRP AEDALEVDTS
210 220
DMTQEQVVAH LLDLVRTRAG ASR
Length:223
Mass (Da):23,443
Last modified:April 29, 2008 - v1
Checksum:i2DD174907CDB149C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU458896 Genomic DNA. Translation: CAM62452.1.

Genome annotation databases

EnsemblBacteriaiCAM62452; CAM62452; MAB_2371.
PATRICi17976472. VBIMycAbs55940_2414.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU458896 Genomic DNA. Translation: CAM62452.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3R8CX-ray2.20A/B2-223[»]
4DIEX-ray2.65A/B/C/D2-223[»]
ProteinModelPortaliB1MB31.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi561007.MAB_2371.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAM62452; CAM62452; MAB_2371.
PATRICi17976472. VBIMycAbs55940_2414.

Phylogenomic databases

eggNOGiENOG4105CAT. Bacteria.
COG0283. LUCA.
HOGENOMiHOG000242850.
OMAiVRARRRY.

Enzyme and pathway databases

BioCyciMABS36809-WGS:GSQO-2384-MONOMER.
MABS561007:GJTG-2384-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00238. Cytidyl_kinase_type1. 1 hit.
InterProiIPR003136. Cytidylate_kin.
IPR011994. Cytidylate_kinase_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF02224. Cytidylate_kin. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00017. cmk. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB1MB31_MYCA9
AccessioniPrimary (citable) accession number: B1MB31
Entry historyi
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: September 7, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.