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B1MAZ4 (B1MAZ4_MYCA9) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phenylalanine--tRNA ligase alpha chain HAMAP MF_00281
EC=6.1.1.20 HAMAP MF_00281
Alternative name(s):
Phenylalanyl-tRNA synthetase alpha chain HAMAP MF_00281
Gene names
Name:pheS HAMAP MF_00281
Ordered Locus Names:MAB_2334
OrganismMycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]
Taxonomic identifier561007 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length351 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe). HAMAP MF_00281

Cofactor

Binds 2 magnesium ions per tetramer By similarity. HAMAP MF_00281

Subunit structure

Tetramer of two alpha and two beta chains By similarity. HAMAP MF_00281

Subcellular location

Cytoplasm By similarity HAMAP MF_00281.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily. HAMAP MF_00281

Sequences

Sequence LengthMass (Da)Tools
B1MAZ4 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 80E3034008870904

FASTA35138,418
        10         20         30         40         50         60 
MADHTQHPSA ESSAELLTTA VDAARAAFDT ADNLDGLAQA KIDHLGEKSP LAQARQALGS 

        70         80         90        100        110        120 
LPKDQRAEAG KLVNAARTQA QQAYDDRLET LRAERDAAVL VAERIDVTLP STRQPLGARH 

       130        140        150        160        170        180 
PITILSENIA DTFIAMGWEV ADGPEVETEH FNFDALNFLP DHPARSTQDT FYIAPEDSRQ 

       190        200        210        220        230        240 
VLRTHTSPVQ VRTLLARELP VYVISLGRAF RTDEIDATHL PAFHQVEGLA VDRGLTLANL 

       250        260        270        280        290        300 
KGTLDAFARA MFGAQAHTRM RPHYFPFTEP SAEVDVWFEN KKGGAGWVEW GGCGMVNPNV 

       310        320        330        340        350 
LRASGIDPGE YSGFAFGMGL ERTLQFRNGL PDMRDMIEGD VRFSLPFGVS A

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References

[1]"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus."
Genoscope
Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU458896 Genomic DNA. Translation: CAM62415.1.
RefSeqYP_001703069.1. NC_010397.1.

3D structure databases

ProteinModelPortalB1MAZ4.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1MAZ4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000006296; EBMYCP00000006235; EBMYCG00000006294.
GeneID5964844.
GenomeReviewsGene locus MAB_2334 in contig CU458896_GR.
KEGGmab:MAB_2334.
PATRIC17976398. VBIMycAbs55940_2377.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000016426.
HOGENOMHBG284353.
OMAFRASYFP.
ProtClustDBPRK00488.

Family and domain databases

HAMAPMF_00281. Phe_tRNA_synth_alpha1.
[Tree]
InterProIPR006195. aa-tRNA-synth_II.
IPR004529. Phe-tRNA-synth_IIc_asu.
IPR004188. Phe-tRNA_synth_II_N.
IPR022911. Phe_tRNA_synth_alpha1_bac.
IPR002319. Phenylalanyl-tRNA_Synthase.
IPR010978. tRNA-bd_arm.
[Graphical view]
KOK01889.
PfamPF02912. Phe_tRNA-synt_N. 1 hit.
PF01409. tRNA-synt_2d. 1 hit.
[Graphical view]
SUPFAMSSF46589. tRNA_binding_arm. 1 hit.
TIGRFAMsTIGR00468. PheS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1MAZ4_MYCA9
AccessionPrimary (citable) accession number: B1MAZ4
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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