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B1M6X8 (B1M6X8_METRJ) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Coproporphyrinogen oxidase EMBL ACB26637.1
EC=1.3.3.3 EMBL ACB26637.1
Gene names
Ordered Locus Names:Mrad2831_4671
OrganismMethylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831) [Complete proteome] [HAMAP]
Taxonomic identifier426355 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length310 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III By similarity. SAAS SAAS018375

Catalytic activity

Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. SAAS SAAS018375

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. SAAS SAAS018375

Subunit structure

Homodimer By similarity. SAAS SAAS018375

Ontologies

Keywords
   Biological processPorphyrin biosynthesis SAAS SAAS018375
   Molecular functionOxidoreductase SAAS SAAS018375 EMBL ACB26637.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processporphyrin-containing compound biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functioncoproporphyrinogen oxidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
B1M6X8 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 50ADE9503F574E72

FASTA31034,504
        10         20         30         40         50         60 
MTMPDDARAA LAAPPSEADV TAMKSEAAAW FETLRDRIVA ALETLEAEAA GPFHPDAPEA 

        70         80         90        100        110        120 
PGTFEKTPWN RTDHTGRPGG GGVMAMLRGR VFEKAGVHIS TVHGEFAPEF RAQMPGAAED 

       130        140        150        160        170        180 
PRFFATGISL IAHPWNPHVP TVHMNTRFVA TTRAWFGGGA DLTPVLDRRR TQEDPDSRHF 

       190        200        210        220        230        240 
HACLERACAA HGIDHARYKA WCDEYFHLKH RNEPRGIGGI FYDYLWSGTP QADLAYTRDV 

       250        260        270        280        290        300 
GRAFLEAYPK IVRDNLGTPW TEADRHEQQV RRGRYVEFNL LYDRGTIFGL KTGGNVASIL 

       310 
SSMPPTVRWP

« Hide

References

[1]"Complete sequence of chromosome of Methylobacterium radiotolerans JCM 2831."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Marx C.J., Richardson P.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27329 / DSM 1819 / JCM 2831.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001001 Genomic DNA. Translation: ACB26637.1.
RefSeqYP_001757320.1. NC_010505.1.

3D structure databases

ProteinModelPortalB1M6X8.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1M6X8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6140738.
GenomeReviewsGene locus Mrad2831_4671 in contig CP001001_GR.
KEGGmrd:Mrad2831_4671.
PATRIC22577784. VBIMetRad70578_4753.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG631180.
OMAVKAYLLD.
ProtClustDBPRK05330.

Family and domain databases

InterProIPR001260. Coprogen_oxidase_aer.
IPR018375. Coprogen_oxidase_CS.
[Graphical view]
Gene3DG3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
KOK00228.
PANTHERPTHR10755. Coprogen_oxidas. 1 hit.
PfamPF01218. Coprogen_oxidas. 1 hit.
[Graphical view]
PIRSFPIRSF000166. Coproporphyri_ox. 1 hit.
PRINTSPR00073. COPRGNOXDASE.
SUPFAMSSF102886. Coprogen_oxidas. 1 hit.
PROSITEPS01021. COPROGEN_OXIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1M6X8_METRJ
AccessionPrimary (citable) accession number: B1M6X8
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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