Skip Header

Contribute Send feedback
Read comments (?) or add your own

B1M517 (B1M517_METRJ) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrA 2 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 2 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401
Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 2 HAMAP MF_01401
Gene names
Name:msrA2 HAMAP MF_01401
Ordered Locus Names:Mrad2831_4512
OrganismMethylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831) [Complete proteome] [HAMAP]
Taxonomic identifier426355 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length218 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401

Catalytic activity

L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site541 By similarity HAMAP MF_01401

Sequences

Sequence LengthMass (Da)Tools
B1M517 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 8B3935B4122C000E

FASTA21823,265
        10         20         30         40         50         60 
MFLFRKRPAM PAPADALPGR PTPIPTAETH VVNGNPLKGP YPPGTGTIVL GLGCFWGAER 

        70         80         90        100        110        120 
RFWQLPEGVF VTAVGYAGGY TPNPTYEEVC TGRTGHNEVV LVAFDPAVLP LEAVVRTFFE 

       130        140        150        160        170        180 
SHDPTQGMRQ GNDVGTQYRS GIYTVGPDQD AAARSVRAAY AEALKARGFP DVTTEIRPLE 

       190        200        210 
QFYFAEAYHQ QYLAKNPAGY CGLGGTGVSC PVGAGVAA

« Hide

References

[1]"Complete sequence of chromosome of Methylobacterium radiotolerans JCM 2831."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Marx C.J., Richardson P.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27329 / DSM 1819 / JCM 2831.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001001 Genomic DNA. Translation: ACB26478.1.
RefSeqYP_001757161.1. NC_010505.1.

3D structure databases

ProteinModelPortalB1M517.
SMRB1M517. Positions 12-211.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1M517.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6140578.
GenomeReviewsGene locus Mrad2831_4512 in contig CP001001_GR.
KEGGmrd:Mrad2831_4512.
PATRIC22577466. VBIMetRad70578_4595.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG748152.
OMASAIYCTS.
ProtClustDBCLSK2331629.

Family and domain databases

HAMAPMF_01401. MsrA.
[Tree]
InterProIPR002569. Peptide_Met_Sox_Rdtase_MsrA.
[Graphical view]
Gene3DG3DSA:3.30.1060.10. MsrA. 1 hit.
KOK07304.
PfamPF01625. PMSR. 1 hit.
[Graphical view]
SUPFAMSSF55068. MsrA. 1 hit.
TIGRFAMsTIGR00401. MsrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB1M517_METRJ
AccessionPrimary (citable) accession number: B1M517
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info