B1M3Y2 (B1M3Y2_METRJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
UDP-3-0-acyl N-acetylglucosamine deacetylase EMBL ACB24859.1

Gene names

Ordered Locus Names:

Mrad2831_2875

Organism

Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831) [Complete proteome] [HAMAP]

Taxonomic identifier

426355 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	300 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS015870
Catalytic activity	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. SAAS SAAS015870
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. SAAS SAAS015870

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS015870 Lipid synthesis
Molecular function	Hydrolase SAAS SAAS015870
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1M3Y2 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: C60DE5896695429A	FASTA	300	32,945
	10 20 30 40 50 60 MHQDVPFPRS TSSAGPRQQA TLAFPFERSG RSLHSGRHAT VRVSPAPAGH GIVFRRHLKD 70 80 90 100 110 120 GRAVDVPAHW HYRESQPLST ALRRDGVLVR TIEHLMASLS ALRIDNVLAE IDADELPIFD 130 140 150 160 170 180 GSATPWCEAI RAAGRREQGL PCRVMRLLRT VAVENGRRRL QIEPGRGLHI TGHVALAHFG 190 200 210 220 230 240 SIDWSGAITP DTFEREIAPA RSFGRYMRAM AGRAYGFMTR NDFLQGVSPR SAALLVRGHV 250 260 270 280 290 300 LGGMRVPGEP VRHRVLDLVG DLALAGHPIE GRICAFHTGH ELNHALVAAL MRDGGAWELV

References

[1]

"Complete sequence of chromosome of Methylobacterium radiotolerans JCM 2831." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Mikhailova N., Marx C.J., Richardson P. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27329 / DSM 1819 / JCM 2831.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001001 Genomic DNA. Translation: ACB24859.1.
RefSeq	YP_001755542.1. NC_010505.1.
3D structure databases
ProteinModelPortal	B1M3Y2.
ModBase	Search...
Protein-protein interaction databases
STRING	B1M3Y2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6138919.
GenomeReviews	Gene locus Mrad2831_2875 in contig CP001001_GR.
KEGG	mrd:Mrad2831_2875.
PATRIC	22574114. VBIMetRad70578_2940.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG482342.
OMA	IAFRRVA.
ProtClustDB	PRK13187.
Family and domain databases
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR004463. UDP-acyl_GlcNac_deAcase. IPR011334. UDP-acyl_GlcNac_deAcase_C. IPR015870. UDP-acyl_N-AcGlcN_deAcase_N. [Graphical view]
Gene3D	G3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit. G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
KO	K02535.
Pfam	PF03331. LpxC. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
ProtoNet	Search...

Entry information

Entry name

B1M3Y2_METRJ

Accession

Primary (citable) accession number: B1M3Y2

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)