ID   B1M363_METRJ            Unreviewed;       357 AA.
AC   B1M363;
DT   29-APR-2008, integrated into UniProtKB/TrEMBL.
DT   29-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 69.
DE   SubName: Full=Metal dependent phosphohydrolase {ECO:0000313|EMBL:ACB24779.1};
GN   OrderedLocusNames=Mrad2831_2795 {ECO:0000313|EMBL:ACB24779.1};
OS   Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 /
OS   NBRC 15690 / NCIMB 10815 / 0-1).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Methylobacteriaceae; Methylobacterium.
OX   NCBI_TaxID=426355 {ECO:0000313|EMBL:ACB24779.1, ECO:0000313|Proteomes:UP000006589};
RN   [1] {ECO:0000313|EMBL:ACB24779.1, ECO:0000313|Proteomes:UP000006589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 /
RC   0-1 {ECO:0000313|Proteomes:UP000006589};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C.,
RA   Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Marx C.J., Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium radiotolerans JCM
RT   2831.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001001; ACB24779.1; -; Genomic_DNA.
DR   RefSeq; WP_012319748.1; NC_010505.1.
DR   AlphaFoldDB; B1M363; -.
DR   STRING; 426355.Mrad2831_2795; -.
DR   KEGG; mrd:Mrad2831_2795; -.
DR   eggNOG; COG2206; Bacteria.
DR   HOGENOM; CLU_000445_92_10_5; -.
DR   OrthoDB; 9802066at2; -.
DR   Proteomes; UP000006589; Chromosome.
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:UniProt.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR037522; HD_GYP_dom.
DR   InterPro; IPR006675; HDIG_dom.
DR   NCBIfam; TIGR00277; HDIG; 1.
DR   PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR   PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR   Pfam; PF13487; HD_5; 1.
DR   SMART; SM00471; HDc; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   PROSITE; PS51831; HD; 1.
DR   PROSITE; PS51832; HD_GYP; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ACB24779.1}.
FT   DOMAIN          166..357
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000259|PROSITE:PS51832"
FT   DOMAIN          188..311
FT                   /note="HD"
FT                   /evidence="ECO:0000259|PROSITE:PS51831"
SQ   SEQUENCE   357 AA;  38406 MW;  FF4D27DEEA78D7B6 CRC64;
     MALGPASRFS DGPFVLIVSD RPSERSALER AIALVMDCRA IPPGIPLPSG RPHLVILDLP
     PARSAELQST LAHHGPPVPR LVLVRGEPLP AARYLRQLPA ASPRQLVLAN VFAMIEEATR
     SAELRQRRLL ERVSGATAVV AEIFDSAALG ARLQRADADR GTELVLAAVS EVGIAEWLTA
     VWRHEIGVYQ HTLGVAGHAA TFGSQIGLGQ TDLALLVRSA LLHDIGKARI PAEILNKPGP
     LNPEESRLMQ RHPDIGADLL RVHGDFEEAV IDVVLHHHER LDGKGYPDRL SGAAISDLVR
     IVTICDVFSA LTERRTYRQP ATPAEALSIM ADNTGHLDPD LLRAFAPSML KGSALAA
//