B1M0P2 (B1M0P2_METRJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA topoisomerase IV, B subunit EMBL ACB23012.1
EC=5.99.1.3 EMBL ACB23012.1

Gene names

Ordered Locus Names:

Mrad2831_1003

Organism

Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831) [Complete proteome] [HAMAP]

Taxonomic identifier

426355 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	686 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the type II topoisomerase family. RuleBase RU000380

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS002288 RuleBase RU000380 Nucleotide-binding
Molecular function	Isomerase Topoisomerase RuleBase RU000380 SAAS SAAS002288
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA topoisomerase (ATP-hydrolyzing) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1M0P2 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 6276FEA0CFC71E07	FASTA	686	74,917
	10 20 30 40 50 60 MSDPARDLFG PGGKGAAARP PEPRRRLDAS ASVATLAAAE PEGGYTASDI EVLEGLEPVR 70 80 90 100 110 120 RRPGMYIGGT DERALHHLFA EVIDNSMDEA VAGHASFIEV ELEESGALVV TDNGRGIPVD 130 140 150 160 170 180 PHPKFPGKSA LEVIMTTLHA GGKFDSKVYE TSGGLHGVGI SVVNALSDLL EVEVARNQTL 190 200 210 220 230 240 YRQTFSRGHA QGALELVGRV QNRRGTRVRF HPDAQIFGSL KFDPRRLFKM ARSKAYLFGG 250 260 270 280 290 300 VEIRWRCAPA LLEGLADVPA EAVHRFPDGL RDYLARDIDG KELVTEAMFS GKITKPGSHG 310 320 330 340 350 360 SLEWAVAWMV AEDGFSHSYC NTIPTPEGGT HEAGLRVALL RGLREHAERV NQAKRMTAVT 370 380 390 400 410 420 TDDVMATCAS MLSVFIREPE FQGQTKDKLA TVEAQRIVET AVRDAFDHWL AASPAQANKL 430 440 450 460 470 480 LDWVIDRAEE RLRRRQEKEV ARKSATRKLR LPGKLADCSA AGTAGSEIFI VEGDSAGGSA 490 500 510 520 530 540 KQARDRATQA ILPLRGKILN VASASRDKLG ANQLISDLTL ALGCGTGTAF RETDLRYEKV 550 560 570 580 590 600 IIMTDADVDG AHIASLLITF FYRQMPKLID RGHLYLAIPP LYRLQQGSKV AYARDDADRE 610 620 630 640 650 660 RIVKTVFKGG KVEIGRFKGL GEMMPAQLKE TTMDPKKRTL LRVAVLDEAR ESTGDTVERL 670 680 MGNKPEARFA FISERAAFAE GADLDI

References

[1]

"Complete sequence of chromosome of Methylobacterium radiotolerans JCM 2831." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Mikhailova N., Marx C.J., Richardson P. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27329 / DSM 1819 / JCM 2831.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001001 Genomic DNA. Translation: ACB23012.1.
RefSeq	YP_001753695.1. NC_010505.1.
3D structure databases
ProteinModelPortal	B1M0P2.
ModBase	Search...
Protein-protein interaction databases
STRING	B1M0P2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6137020.
GenomeReviews	Gene locus Mrad2831_1003 in contig CP001001_GR.
KEGG	mrd:Mrad2831_1003.
PATRIC	22570270. VBIMetRad70578_1044.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304889.
OMA	QARDKEF.
ProtClustDB	PRK05559.
Family and domain databases
InterPro	IPR003594. ATPase-like_ATP-bd. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR001241. Topo_IIA. IPR013759. Topo_IIA_B/N_ab. IPR002288. Topo_IIA_B_C. IPR013506. Topo_IIA_bsu_dom2. IPR013760. Topo_IIA_cen. IPR018522. TopoIIA_CS. IPR005737. TopoIV_B_Gneg. IPR006171. Toprim_domain. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit. G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 1 hit.
KO	K02622.
Pfam	PF00204. DNA_gyraseB. 1 hit. PF00986. DNA_gyraseB_C. 1 hit. PF02518. HATPase_c. 1 hit. PF01751. Toprim. 1 hit. [Graphical view]
PRINTS	PR00418. TPI2FAMILY.
SMART	SM00387. HATPase_c. 1 hit. SM00433. TOP2c. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMs	TIGR01055. ParE_Gneg. 1 hit.
PROSITE	PS00177. TOPOISOMERASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B1M0P2_METRJ

Accession

Primary (citable) accession number: B1M0P2

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)