B1LZY1 (URED1_METRJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Urease accessory protein UreD 1

Gene names

Name:	ureD1
Ordered Locus Names:	Mrad2831_2469

Organism

Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831) [Complete proteome] [HAMAP]

Taxonomic identifier

426355 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	288 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter By similarity. HAMAP MF_01384
Subunit structure	UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_01384.
Sequence similarities	Belongs to the UreD family.

Ontologies

Keywords
Biological process	Nickel insertion
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nickel cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 288	288	Urease accessory protein UreD 1 HAMAP MF_01384		PRO_0000346578

Sequences

	Sequence		Length	Mass (Da)
	B1LZY1 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 7EF8B377F7B7F8CD	FASTA	288	29,968
	10 20 30 40 50 60 MHGPLAPAPS PERLGAAPAR QRSDGRIRLR VGPARPGGGT RILDLAEAGP SRLRFPRGTC 70 80 90 100 110 120 ALEAVLVNTA GGVACGDSFA IDLALEPGAD LVLTTTAAEK IYRSDGPVSR IANTLTLGEG 130 140 150 160 170 180 AGLAWLPQET ILFDRARVRR RFEADLADGA ALIAAEVVAF GRAARGERIV DGLFADSWRI 190 200 210 220 230 240 RRGGRLAYAD SVLLEGPISD HLARPAIGGG ARACATILDV SPGAEARLEE ARARLAEAAS 250 260 270 280 PGTTAAASAW NGHLAVRALG DAVGPLRGLV ARFLAGYRAL PMPRVWQS

References

[1]

"Complete sequence of chromosome of Methylobacterium radiotolerans JCM 2831." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Mikhailova N., Marx C.J., Richardson P. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27329 / DSM 1819 / JCM 2831.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001001 Genomic DNA. Translation: ACB24464.1.
RefSeq	YP_001755147.1. NC_010505.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B1LZY1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6138511.
GenomeReviews	Gene locus Mrad2831_2469 in contig CP001001_GR.
KEGG	mrd:Mrad2831_2469.
PATRIC	22573322. VBIMetRad70578_2547.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG711156.
OMA	QETILFD.
ProtClustDB	CLSK980186.
Family and domain databases
HAMAP	MF_01384. UreD. [Tree]
InterPro	IPR002669. UreD. [Graphical view]
KO	K03190.
Pfam	PF01774. UreD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

URED1_METRJ

Accession

Primary (citable) accession number: B1LZY1

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 2, 2008
Last sequence update:	April 29, 2008
Last modified:	January 25, 2012
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program