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Protein

NAD(P)H dehydrogenase (quinone)

Gene

Mrad2831_3831

Organism
Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

NAD(P)H + a quinone = NAD(P)+ + a hydroquinone.UniRule annotation

Cofactori

FMNUniRule annotationNote: Binds 1 FMN per monomer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei12NAD(P)UniRule annotation1
Binding sitei98SubstrateUniRule annotation1
Binding sitei134FMNUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 15FMNUniRule annotation6
Nucleotide bindingi78 – 80FMNUniRule annotation3
Nucleotide bindingi113 – 119FMNUniRule annotation7

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandFlavoprotein, FMN, NAD, NADP, Nucleotide-binding

Enzyme and pathway databases

BioCyciMRAD426355:GJB5-3825-MONOMER

Protein family/group databases

CAZyiAA6 Auxiliary Activities 6

Names & Taxonomyi

Protein namesi
Recommended name:
NAD(P)H dehydrogenase (quinone)UniRule annotation (EC:1.6.5.2UniRule annotation)
Alternative name(s):
Flavoprotein WrbA
NAD(P)H:quinone oxidoreductaseUniRule annotation
Short name:
NQOUniRule annotation
Gene namesi
Ordered Locus Names:Mrad2831_3831
OrganismiMethylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1)
Taxonomic identifieri426355 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
Proteomesi
  • UP000006589 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002006351 – 200NAD(P)H dehydrogenase (quinone)Add BLAST200

Interactioni

Protein-protein interaction databases

STRINGi426355.Mrad2831_3831

Structurei

3D structure databases

ProteinModelPortaliB1LY35
SMRiB1LY35
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 190Flavodoxin-likeUniRule annotationAdd BLAST187

Sequence similaritiesi

Belongs to the WrbA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CS1 Bacteria
COG0655 LUCA
HOGENOMiHOG000030539
KOiK03809
OMAiVGVPYAC
OrthoDBiPOG091H03V0

Family and domain databases

Gene3Di3.40.50.360, 1 hit
HAMAPiMF_01017 NQOR, 1 hit
InterProiView protein in InterPro
IPR008254 Flavodoxin/NO_synth
IPR029039 Flavoprotein-like_sf
IPR010089 Flavoprotein_WrbA-like
IPR005025 FMN_Rdtase-like
IPR037513 NQO
PfamiView protein in Pfam
PF03358 FMN_red, 1 hit
SUPFAMiSSF52218 SSF52218, 1 hit
TIGRFAMsiTIGR01755 flav_wrbA, 1 hit
PROSITEiView protein in PROSITE
PS50902 FLAVODOXIN_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

B1LY35-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKVLVLYYS TYGHVEQMAY AVAEGARETG AEVVVKRVPE LVPEEVARQN
60 70 80 90 100
HFKLDQAAPV ATVAELADYD AIIFGTPTRY GNMASQMKQF IDQTGGLWMK
110 120 130 140 150
GALVGKVGSV FTSTASQHGG QETTLTSFHT VLFHHGMVVV GLPYSFQGQA
160 170 180 190 200
GVEAVKGNTP YGASTIADGD GSRQPSAVEL EGARFQGRHV AGIAAKLARD
Length:200
Mass (Da):21,274
Last modified:April 29, 2008 - v1
Checksum:iB16D5801F08A62D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001001 Genomic DNA Translation: ACB25806.1
RefSeqiWP_012320764.1, NC_010505.1

Genome annotation databases

EnsemblBacteriaiACB25806; ACB25806; Mrad2831_3831
GeneIDi6139885
KEGGimrd:Mrad2831_3831

Similar proteinsi

Entry informationi

Entry nameiNQOR_METRJ
AccessioniPrimary (citable) accession number: B1LY35
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: May 23, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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