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Protein

Superoxide dismutase [Cu-Zn]

Gene

Mrad2831_3819

Organism
Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandCopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

BioCyciMRAD426355:GJB5-3813-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Mrad2831_3819Imported
OrganismiMethylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831)Imported
Taxonomic identifieri426355 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
Proteomesi
  • UP000006589 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500276606222 – 179Superoxide dismutase [Cu-Zn]Sequence analysisAdd BLAST158

Interactioni

Protein-protein interaction databases

STRINGi426355.Mrad2831_3819

Structurei

3D structure databases

ProteinModelPortaliB1LY23
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 178Sod_CuInterPro annotationAdd BLAST136

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4108Z7T Bacteria
COG2032 LUCA
HOGENOMiHOG000263448
KOiK04565
OMAiGKSVIIH
OrthoDBiPOG091H05EB

Family and domain databases

Gene3Di2.60.40.200, 1 hit
InterProiView protein in InterPro
IPR036423 SOD-like_Cu/Zn_dom_sf
IPR024134 SOD_Cu/Zn_/chaperone
IPR018152 SOD_Cu/Zn_BS
IPR001424 SOD_Cu_Zn_dom
PANTHERiPTHR10003 PTHR10003, 1 hit
PfamiView protein in Pfam
PF00080 Sod_Cu, 1 hit
SUPFAMiSSF49329 SSF49329, 1 hit
PROSITEiView protein in PROSITE
PS00087 SOD_CU_ZN_1, 1 hit
PS00332 SOD_CU_ZN_2, 1 hit

Sequencei

Sequence statusi: Complete.

B1LY23-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRTLPLLAL LGTAAAGGAL AQEPPKEAAK PAETYTAPIK NAKGDPIGTL
60 70 80 90 100
AIRDGANTLV LRVTIQPGGL PPGWHGMHFH AVGDCSDPKF MNSKAHVNHD
110 120 130 140 150
QSKHGLLNAE GPDEGDLPNL YAAQDGSANA EVSSETPLNG EGGLKDGDGA
160 170
ALIIHANEDD HNTQPIGGAG DRIACGVIK
Length:179
Mass (Da):18,316
Last modified:April 29, 2008 - v1
Checksum:i21C6EBD668D9E780
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001001 Genomic DNA Translation: ACB25794.1
RefSeqiWP_012320752.1, NC_010505.1

Genome annotation databases

EnsemblBacteriaiACB25794; ACB25794; Mrad2831_3819
GeneIDi6139873
KEGGimrd:Mrad2831_3819

Similar proteinsi

Entry informationi

Entry nameiB1LY23_METRJ
AccessioniPrimary (citable) accession number: B1LY23
Entry historyiIntegrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: March 28, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health