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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei142GTPUniRule annotation1
Binding sitei146GTPUniRule annotation1
Binding sitei190GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi24 – 28GTPUniRule annotation5
Nucleotide bindingi111 – 113GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:Mrad2831_2350Imported
OrganismiMethylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1)Imported
Taxonomic identifieri426355 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
Proteomesi
  • UP000006589 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi426355.Mrad2831_2350

Structurei

3D structure databases

ProteinModelPortaliB1LXY8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 208TubulinInterPro annotationAdd BLAST193
Domaini210 – 328Tubulin_CInterPro annotationAdd BLAST119

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili334 – 354Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiRAVMREM
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR017844 Cell_div_FtsZ_C
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
TIGR03483 FtsZ_alphas_C, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

B1LXY8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAITLQAPDI RELKPRITVF GVGGAGGNAV NNMIESGLLG CEFVVANTDA
60 70 80 90 100
QALTSSKAER VIQMGLGVTQ GLGAGSHPEV GSAAADEVID EIRDQLSGAH
110 120 130 140 150
MCFITAGMGG GTGTGAAPVI ARAARDMGIL TVGVVTKPFQ FEGMRRMRTA
160 170 180 190 200
ESGIQELQAA VDTLIVIPNQ NLFRVANEKT TFADAFAMAD QVLYSGVACI
210 220 230 240 250
TDLMVKEGLI NLDFADVRAI MRGMGKAMMG TGEASGEKRA NRAAEAAIAN
260 270 280 290 300
PLLDDVSMKG ARGLLISITG GSDLTLYELD EAATRIREEV DQDANIILGA
310 320 330 340 350
TFDESLDGII RVSVVATGIE PALISANSPN NPAIAETEQR IAEVAERLRA
360 370 380 390 400
EARSRAASPV PSIRTESVAP APSSAPAPAP LSAPEMRPES RMDARIEAAA
410 420 430 440 450
PVTRDDVVLA PVQARAAAPF VPAPAPQRVE AAPAVEAGPF VPPRPAAPTG
460 470 480 490 500
TPLARAPRMP QIHELPPIAQ TQIMANRAAE ETAPESKRTS LLRRLATVGF
510 520 530 540 550
GGRREDMDGA PAARPASAVA PQPHMGQPHM GQPHVPPAPR APAAPAVPQY
560 570 580
RPVQGNLDAQ GRVAPQPRMM DDDQLEIPAF LRRQAN
Length:586
Mass (Da):61,278
Last modified:April 29, 2008 - v1
Checksum:i0C59573823F4EB5E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001001 Genomic DNA Translation: ACB24345.1
RefSeqiWP_012319318.1, NC_010505.1

Genome annotation databases

EnsemblBacteriaiACB24345; ACB24345; Mrad2831_2350
GeneIDi6138382
KEGGimrd:Mrad2831_2350
PATRICifig|426355.14.peg.2417

Similar proteinsi

Entry informationi

Entry nameiB1LXY8_METRJ
AccessioniPrimary (citable) accession number: B1LXY8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: May 23, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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