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Protein

Trans-aconitate 2-methyltransferase

Gene

tam

Organism
Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + trans-aconitate = S-adenosyl-L-homocysteine + (E)-3-(methoxycarbonyl)pent-2-enedioate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciMRAD426355:GJB5-5392-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Trans-aconitate 2-methyltransferaseUniRule annotation (EC:2.1.1.144UniRule annotation)
Gene namesi
Name:tamUniRule annotation
Ordered Locus Names:Mrad2831_5330
OrganismiMethylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831)
Taxonomic identifieri426355 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
Proteomesi
  • UP000006589 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 260260Trans-aconitate 2-methyltransferasePRO_1000129260Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi426355.Mrad2831_5330.

Structurei

3D structure databases

ProteinModelPortaliB1LXF6.
SMRiB1LXF6. Positions 8-259.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. Tam family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107R6G. Bacteria.
COG4106. LUCA.
HOGENOMiHOG000125295.
KOiK00598.
OMAiARVDVWR.
OrthoDBiEOG6716PV.

Family and domain databases

Gene3Di1.10.150.290. 2 hits.
3.40.50.150. 1 hit.
HAMAPiMF_00560. Tran_acon_Me_trans.
InterProiIPR029063. SAM-dependent_MTases.
IPR023506. Trans-aconitate_MeTrfase.
IPR023149. Trans_acon_MeTrfase_C.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

B1LXF6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADWNPALYT RFEDERTRPA AELLARVPLE APRLAIDLGC GPGNSTALIA
60 70 80 90 100
ARFPDAEVIG LDTSPAMLES ARARLPRLAF ALADAATWTP ERAPDLIYAN
110 120 130 140 150
AVLQWLPDHA TLLPRLFGLL APGGVLAVQM PDNLAEPTHR LMRAVAASGP
160 170 180 190 200
WAAAIGDPAV AGRLGRMLEP AAYYDLLAPA AAEVDVWRTA YHHRMADAAA
210 220 230 240 250
IVDWVRATGL RPFLDPLDPE HRAGFLDAYT RAIDGAYPPR SDGRRLLAFP
260
RVFVVARKAS
Length:260
Mass (Da):28,139
Last modified:April 29, 2008 - v1
Checksum:iC186A2AB85BB0851
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001001 Genomic DNA. Translation: ACB27277.1.
RefSeqiWP_012322221.1. NC_010505.1.

Genome annotation databases

EnsemblBacteriaiACB27277; ACB27277; Mrad2831_5330.
GeneIDi6141402.
KEGGimrd:Mrad2831_5330.
PATRICi22579056. VBIMetRad70578_5384.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001001 Genomic DNA. Translation: ACB27277.1.
RefSeqiWP_012322221.1. NC_010505.1.

3D structure databases

ProteinModelPortaliB1LXF6.
SMRiB1LXF6. Positions 8-259.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi426355.Mrad2831_5330.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACB27277; ACB27277; Mrad2831_5330.
GeneIDi6141402.
KEGGimrd:Mrad2831_5330.
PATRICi22579056. VBIMetRad70578_5384.

Phylogenomic databases

eggNOGiENOG4107R6G. Bacteria.
COG4106. LUCA.
HOGENOMiHOG000125295.
KOiK00598.
OMAiARVDVWR.
OrthoDBiEOG6716PV.

Enzyme and pathway databases

BioCyciMRAD426355:GJB5-5392-MONOMER.

Family and domain databases

Gene3Di1.10.150.290. 2 hits.
3.40.50.150. 1 hit.
HAMAPiMF_00560. Tran_acon_Me_trans.
InterProiIPR029063. SAM-dependent_MTases.
IPR023506. Trans-aconitate_MeTrfase.
IPR023149. Trans_acon_MeTrfase_C.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Methylobacterium radiotolerans JCM 2831."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.
    , Kyrpides N., Mikhailova N., Marx C.J., Richardson P.
    Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27329 / DSM 1819 / JCM 2831.

Entry informationi

Entry nameiTAM_METRJ
AccessioniPrimary (citable) accession number: B1LXF6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: November 11, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.