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Protein

Trans-aconitate 2-methyltransferase

Gene

tam

Organism
Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + trans-aconitate = S-adenosyl-L-homocysteine + (E)-3-(methoxycarbonyl)pent-2-enedioate.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Trans-aconitate 2-methyltransferaseUniRule annotation (EC:2.1.1.144UniRule annotation)
Gene namesi
Name:tamUniRule annotation
Ordered Locus Names:Mrad2831_5330
OrganismiMethylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1)
Taxonomic identifieri426355 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
Proteomesi
  • UP000006589 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001292601 – 260Trans-aconitate 2-methyltransferaseAdd BLAST260

Interactioni

Protein-protein interaction databases

STRINGi426355.Mrad2831_5330

Structurei

3D structure databases

ProteinModelPortaliB1LXF6
SMRiB1LXF6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. Tam family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107R6G Bacteria
COG4106 LUCA
HOGENOMiHOG000125295
KOiK00598
OMAiGPWADKL
OrthoDBiPOG091H08XS

Family and domain databases

Gene3Di1.10.150.290, 2 hits
HAMAPiMF_00560 Tran_acon_Me_trans, 1 hit
InterProiView protein in InterPro
IPR029063 SAM-dependent_MTases
IPR023506 Trans-aconitate_MeTrfase
IPR023149 Trans_acon_MeTrfase_C
SUPFAMiSSF53335 SSF53335, 1 hit

Sequencei

Sequence statusi: Complete.

B1LXF6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADWNPALYT RFEDERTRPA AELLARVPLE APRLAIDLGC GPGNSTALIA
60 70 80 90 100
ARFPDAEVIG LDTSPAMLES ARARLPRLAF ALADAATWTP ERAPDLIYAN
110 120 130 140 150
AVLQWLPDHA TLLPRLFGLL APGGVLAVQM PDNLAEPTHR LMRAVAASGP
160 170 180 190 200
WAAAIGDPAV AGRLGRMLEP AAYYDLLAPA AAEVDVWRTA YHHRMADAAA
210 220 230 240 250
IVDWVRATGL RPFLDPLDPE HRAGFLDAYT RAIDGAYPPR SDGRRLLAFP
260
RVFVVARKAS
Length:260
Mass (Da):28,139
Last modified:April 29, 2008 - v1
Checksum:iC186A2AB85BB0851
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001001 Genomic DNA Translation: ACB27277.1
RefSeqiWP_012322221.1, NC_010505.1

Genome annotation databases

EnsemblBacteriaiACB27277; ACB27277; Mrad2831_5330
GeneIDi6141402
KEGGimrd:Mrad2831_5330

Similar proteinsi

Entry informationi

Entry nameiTAM_METRJ
AccessioniPrimary (citable) accession number: B1LXF6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: May 23, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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