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B1LUS0 (GLSA_METRJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutaminase
EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:Mrad2831_3529
OrganismMethylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831) [Complete proteome] [HAMAP]
Taxonomic identifier426355 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium ›

Protein attributes

Sequence length309 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity.

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 309309Glutaminase HAMAP-Rule MF_00313
PRO_1000115698

Sites

Binding site641Substrate By similarity
Binding site1141Substrate By similarity
Binding site1601Substrate By similarity
Binding site1671Substrate By similarity
Binding site1911Substrate By similarity
Binding site2431Substrate By similarity
Binding site2611Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
B1LUS0 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 8674227C6EA2F188

FASTA30933,255
        10         20         30         40         50         60 
MPDLAHVIRE ISEEMAQRSD RGAVADYIPE LARVDPDQFG MAVIDAEGQV FTGGDSETPF 

        70         80         90        100        110        120 
SIQSVSKVFT LTLALGMVGD RLWKRVGREP SGNPFNSIVQ LERERGVPRN PFINAGAIAV 

       130        140        150        160        170        180 
TDVILSGHEP REALGEILRF MQFLAQDSGI IIDETVAASE KRTGFRNTAL ANYMKSFGVI 

       190        200        210        220        230        240 
DNPVDYTLGV YFHHCAIAMN CRQLARAGRF LAHNGVNPST GHSVVSAERA RRINAIMLTC 

       250        260        270        280        290        300 
GHYDGSGEFA YRVGLPGKSG VGGSILAIAP GKASIAVWSP GLDAAGNSHL GRIALERLTQ 


RMGWSVFGA

« Hide

References

[1]"Complete sequence of chromosome of Methylobacterium radiotolerans JCM 2831."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Marx C.J., Richardson P.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27329 / DSM 1819 / JCM 2831.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001001 Genomic DNA. Translation: ACB25506.1.
RefSeqYP_001756189.1. NC_010505.1.

3D structure databases

ProteinModelPortalB1LUS0.
ModBaseSearch...

Protein-protein interaction databases

STRING426355.Mrad2831_3529.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACB25506; ACB25506; Mrad2831_3529.
GeneID6139582.
KEGGmrd:Mrad2831_3529.
PATRIC22575468. VBIMetRad70578_3609.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMAEPSGNPF.
ProtClustDBPRK00971.

Enzyme and pathway databases

BioCycMRAD426355:GJB5-3572-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. PBP_transp_fold. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_METRJ
AccessionPrimary (citable) accession number: B1LUS0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 29, 2008
Last modified: May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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