B1LUJ1 (B1LUJ1_METRJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	Mrad2831_2014

Organism

Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831) [Complete proteome] [HAMAP]

Taxonomic identifier

426355 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	1096 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1LUJ1 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 53D44EDD3506E7B2	FASTA	1,096	120,808
	10 20 30 40 50 60 MTAPQLPYAE LAVTTNFSFL HGAAHPQEFV AQAASYGLEA IGIADRNTVA GVVRAHAAAR 70 80 90 100 110 120 ALEPQGTAIR ILPGVRLVTE EGFEAVTYPM DREAWGRLCR LLTLGNRRVR KGDCRFAFAE 130 140 150 160 170 180 MLEASEGQMF IAMPPARRLP EGFRARLEAL AAAAPGRTFL GASHTRRGDE RRRLGLLAEL 190 200 210 220 230 240 GAASGAPMVA VSDALYHHPD RRPLQDVVTC IREGCRIEDA GYRLEANAER HLKPPPEMAR 250 260 270 280 290 300 LFADHPEALV RTVEIAQACA FDLAQLRYEY PDEPVPPGRT PQEYLEEKTW ERARWRYAGE 310 320 330 340 350 360 VPDAVAATLR EELRLIAKMD YARYFLTLFD VVEFARGRGI LCQGRGSAAN SAVCFCLGIT 370 380 390 400 410 420 AVDPSKHRLL FARFISENRG EPPDIDVDFE HERREEVIQH LYARYGRERA ALCATVIHYR 430 440 450 460 470 480 PRMAIREVGK VLGLTEDVTA AIADTVWGSW GTGMPDRHVR EAGLDPENPA IRQALDLAHQ 490 500 510 520 530 540 LIGFPRHLSQ HVGGFVLTRG RLDETVPVGN GAMADRTFIE WDKDDIDAIG LMKVDVLALG 550 560 570 580 590 600 MLTCLKRGLD FLERDHGTLY ATLADLPQDD PATYAMLAKA DSVGVFQVES RAQMSMLPRL 610 620 630 640 650 660 KPKEFYDLVV QVAIVRPGPI QGDMVHPYLR RRSGIDPVEY PAPHPDHGPA DELKEVLQKT 670 680 690 700 710 720 YGVPLFQEHA MQIAITAAGF TPAEADGLRR AMATFRHVGS IGGFADKFVG GMTRRGYPKD 730 740 750 760 770 780 FAERCFAQIR GFSTYGFPES HAASFALLVY ASAWMKCRHP DVFLAAILNA QPMGFYQPAQ 790 800 810 820 830 840 LVRDARAHGV EVRGVCVNAS DWDCTLEPGG NPALHAVRIG LRAVRGLPEA AMRRLVRLRA 850 860 870 880 890 900 NGYASIEGLQ ASLALPRNAL ERLAEADAFR SLGLDRRAAL WMVRTLEGTS ARKAARADPS 910 920 930 940 950 960 ERRAHLLDAP LPLFAWHSDD GLFRHEPAVD LPALAPSEAV AEDYSATGLS LQGHPVAFFR 970 980 990 1000 1010 1020 GRLARIGAIP ARAHLDPALP QGARVTVAGL VLIRQRPGTA KGVVFLTLED ETGIANVIVW 1030 1040 1050 1060 1070 1080 KAVFEANRRA AMQARFLAVR GRIQRADGVV HLVAEGFRDL TASLGDLREA GMRLPPETTD 1090 FGVPPDRRVY RSRDFH

References

[1]

"Complete sequence of chromosome of Methylobacterium radiotolerans JCM 2831." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Mikhailova N., Marx C.J., Richardson P. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27329 / DSM 1819 / JCM 2831.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001001 Genomic DNA. Translation: ACB24009.1.
RefSeq	YP_001754692.1. NC_010505.1.
3D structure databases
ProteinModelPortal	B1LUJ1.
ModBase	Search...
Protein-protein interaction databases
STRING	B1LUJ1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6138043.
GenomeReviews	Gene locus Mrad2831_2014 in contig CP001001_GR.
KEGG	mrd:Mrad2831_2014.
PATRIC	22572348. VBIMetRad70578_2072.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734490.
OMA	MFQIESP.
ProtClustDB	CLSK891351.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1LUJ1_METRJ

Accession

Primary (citable) accession number: B1LUJ1

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)