Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B1LR29

- MUTH_ECOSM

UniProt

B1LR29 - MUTH_ECOSM

Protein

DNA mismatch repair protein MutH

Gene

mutH

Organism
Escherichia coli (strain SMS-3-5 / SECEC)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (29 Apr 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.UniRule annotation

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. endonuclease activity Source: UniProtKB-KW

    GO - Biological processi

    1. DNA modification Source: InterPro
    2. DNA repair Source: UniProtKB-KW

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    DNA damage, DNA repair

    Enzyme and pathway databases

    BioCyciECOL439855:GHHB-2975-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA mismatch repair protein MutHUniRule annotation
    Alternative name(s):
    Methyl-directed mismatch repair proteinUniRule annotation
    Gene namesi
    Name:mutHUniRule annotation
    Ordered Locus Names:EcSMS35_2979
    OrganismiEscherichia coli (strain SMS-3-5 / SECEC)
    Taxonomic identifieri439855 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000007011: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 229229DNA mismatch repair protein MutHPRO_1000133467Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi439855.EcSMS35_2979.

    Structurei

    3D structure databases

    ProteinModelPortaliB1LR29.
    SMRiB1LR29. Positions 3-229.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the MutH family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG3066.
    HOGENOMiHOG000271839.
    KOiK03573.
    OMAiLRPKGAN.
    OrthoDBiEOG6CGCC0.

    Family and domain databases

    Gene3Di3.40.600.10. 1 hit.
    HAMAPiMF_00759. MutH.
    InterProiIPR004230. DNA_mismatch_repair_MutH.
    IPR011337. DNA_rep_MutH/RE_typeII.
    IPR011335. Restrct_endonuc-II-like.
    [Graphical view]
    PfamiPF02976. MutH. 1 hit.
    [Graphical view]
    SMARTiSM00927. MutH. 1 hit.
    [Graphical view]
    SUPFAMiSSF52980. SSF52980. 1 hit.
    TIGRFAMsiTIGR02248. mutH_TIGR. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B1LR29-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSQPRPLLSP PETEEQLLAQ AQQLSGYTLG ELAALAGLVT PENLKRDKGW    50
    IGVLLEIWLG ASAGSKPEQD FAALGVELKT IPVDSLGRPL ETTFVCVAPL 100
    TGNSGVTWET SHVRHKLKRV LWIPVEGERS IPLAQRRVGS PLLWSPNEEE 150
    DRQLREDWEE LMDMIVLGQV ERITARHGEY LQIRPKAANA KALTEAIGVR 200
    GERILTLPRG FYLKKNFTSA LLARHFLIQ 229
    Length:229
    Mass (Da):25,527
    Last modified:April 29, 2008 - v1
    Checksum:i7EC2BD945E963A9C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000970 Genomic DNA. Translation: ACB16837.1.
    RefSeqiYP_001745000.1. NC_010498.1.

    Genome annotation databases

    EnsemblBacteriaiACB16837; ACB16837; EcSMS35_2979.
    GeneIDi6145783.
    KEGGiecm:EcSMS35_2979.
    PATRICi18434870. VBIEscCol6161_3131.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000970 Genomic DNA. Translation: ACB16837.1 .
    RefSeqi YP_001745000.1. NC_010498.1.

    3D structure databases

    ProteinModelPortali B1LR29.
    SMRi B1LR29. Positions 3-229.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 439855.EcSMS35_2979.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACB16837 ; ACB16837 ; EcSMS35_2979 .
    GeneIDi 6145783.
    KEGGi ecm:EcSMS35_2979.
    PATRICi 18434870. VBIEscCol6161_3131.

    Phylogenomic databases

    eggNOGi COG3066.
    HOGENOMi HOG000271839.
    KOi K03573.
    OMAi LRPKGAN.
    OrthoDBi EOG6CGCC0.

    Enzyme and pathway databases

    BioCyci ECOL439855:GHHB-2975-MONOMER.

    Family and domain databases

    Gene3Di 3.40.600.10. 1 hit.
    HAMAPi MF_00759. MutH.
    InterProi IPR004230. DNA_mismatch_repair_MutH.
    IPR011337. DNA_rep_MutH/RE_typeII.
    IPR011335. Restrct_endonuc-II-like.
    [Graphical view ]
    Pfami PF02976. MutH. 1 hit.
    [Graphical view ]
    SMARTi SM00927. MutH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52980. SSF52980. 1 hit.
    TIGRFAMsi TIGR02248. mutH_TIGR. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Insights into the environmental resistance gene pool from the genome sequence of the multidrug-resistant environmental isolate Escherichia coli SMS-3-5."
      Fricke W.F., Wright M.S., Lindell A.H., Harkins D.M., Baker-Austin C., Ravel J., Stepanauskas R.
      J. Bacteriol. 190:6779-6794(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SMS-3-5 / SECEC.

    Entry informationi

    Entry nameiMUTH_ECOSM
    AccessioniPrimary (citable) accession number: B1LR29
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: April 29, 2008
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3