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B1LPF1 (B1LPF1_ECOSM) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonucleoside-diphosphate reductase subunit beta PIRNR PIRNR000355
EC=1.17.4.1 PIRNR PIRNR000355
Gene names
Name:nrdF EMBL ACB19933.1
Ordered Locus Names:EcSMS35_2798 EMBL ACB19933.1
OrganismEscherichia coli (strain SMS-3-5 / SECEC) [Complete proteome] [HAMAP] EMBL ACB19933.1
Taxonomic identifier439855 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length319 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides By similarity. PIRNR PIRNR000355

Catalytic activity

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. PIRNR PIRNR000355

Cofactor

Binds 2 iron ions per subunit By similarity. PIRNR PIRNR000355

Pathway

Genetic information processing; DNA replication. PIRNR PIRNR000355

Sequence similarities

Belongs to the ribonucleoside diphosphate reductase small chain family. PIRNR PIRNR000355

Sequences

Sequence LengthMass (Da)Tools
B1LPF1 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: CDC40017D5B61D5E

FASTA31936,455
        10         20         30         40         50         60 
MKLSRISAIN WNKISDDKDL EVWNRLTSNF WLPEKVPLSN DIPAWQTLSV VEQQLTMRVF 

        70         80         90        100        110        120 
TGLTLLDTLQ NVIGAPSLMP DALTPHEEAV LSNISFMEAV HARSYSSIFS TLCQTKDVDA 

       130        140        150        160        170        180 
AYAWSEENAP LQRKAQIIQQ HYRGDDPLKK KIASVFLESF LFYSGFWLPM YFSSRGKLTN 

       190        200        210        220        230        240 
TADLIRLIIR DEAVHGYYIG YKYQKKLEKI SLAQREELKS FAFDLLLELY DNELQYTDEL 

       250        260        270        280        290        300 
YAETPWSDDV KAFLCYNANK ALMNLGYEPL FPAEMAEVNP AILAALSPNA DENHDFFSGS 

       310 
GSSYVMGKAV ETEDEDWNF

« Hide

References

[1]"Insights into the environmental resistance gene pool from the genome sequence of the multidrug-resistant environmental isolate Escherichia coli SMS-3-5."
Fricke W.F., Wright M.S., Lindell A.H., Harkins D.M., Baker-Austin C., Ravel J., Stepanauskas R.
J. Bacteriol. 190:6779-6794(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SMS-3-5 / SECEC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000970 Genomic DNA. Translation: ACB19933.1.
RefSeqYP_001744827.1. NC_010498.1.

3D structure databases

ProteinModelPortalB1LPF1.
SMRB1LPF1. Positions 4-318.
ModBaseSearch...

Protein-protein interaction databases

STRING439855.EcSMS35_2798.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACB19933; ACB19933; EcSMS35_2798.
GeneID6142946.
KEGGecm:EcSMS35_2798.
PATRIC18434504. VBIEscCol6161_2956.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0208.
HOGENOMHOG000246153.
KOK00526.
OMAIGYKYQR.
ProtClustDBPRK09614.

Enzyme and pathway databases

BioCycECOL439855:GHHB-2795-MONOMER.
UniPathwayUPA00326.

Family and domain databases

Gene3D1.10.620.20. 1 hit.
InterProIPR009078. Ferritin-like_SF.
IPR012348. RNR-rel.
IPR026494. RNR_1b_NrdF.
IPR026023. RNR_bsu_prok.
IPR000358. RNR_small.
[Graphical view]
PANTHERPTHR23409. PTHR23409. 1 hit.
PfamPF00268. Ribonuc_red_sm. 1 hit.
[Graphical view]
PIRSFPIRSF000355. NrdB. 1 hit.
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
TIGRFAMsTIGR04171. RNR_1b_NrdF. 1 hit.
PROSITEPS00368. RIBORED_SMALL. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1LPF1_ECOSM
AccessionPrimary (citable) accession number: B1LPF1
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: May 29, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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