Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B1LLG1

- SUCC_ECOSM

UniProt

B1LLG1 - SUCC_ECOSM

Protein

Succinyl-CoA ligase [ADP-forming] subunit beta

Gene

sucC

Organism
Escherichia coli (strain SMS-3-5 / SECEC)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (29 Apr 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + succinate + CoA = ADP + phosphate + succinyl-CoA.UniRule annotation

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi197 – 1971Magnesium or manganeseUniRule annotation
    Metal bindingi199 – 1991Magnesium or manganeseUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi35 – 10874ATPUniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. magnesium ion binding Source: UniProtKB-HAMAP
    3. manganese ion binding Source: UniProtKB-HAMAP
    4. succinate-CoA ligase (ADP-forming) activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. tricarboxylic acid cycle Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Tricarboxylic acid cycle

    Keywords - Ligandi

    ATP-binding, Magnesium, Manganese, Metal-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciECOL439855:GHHB-738-MONOMER.
    UniPathwayiUPA00223; UER00999.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Succinyl-CoA ligase [ADP-forming] subunit betaUniRule annotation (EC:6.2.1.5UniRule annotation)
    Alternative name(s):
    Succinyl-CoA synthetase subunit betaUniRule annotation
    Short name:
    SCS-betaUniRule annotation
    Gene namesi
    Name:sucCUniRule annotation
    Ordered Locus Names:EcSMS35_0740
    OrganismiEscherichia coli (strain SMS-3-5 / SECEC)
    Taxonomic identifieri439855 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000007011: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 388388Succinyl-CoA ligase [ADP-forming] subunit betaPRO_1000129188Add
    BLAST

    Proteomic databases

    PRIDEiB1LLG1.

    Interactioni

    Subunit structurei

    Heterotetramer of two alpha and two beta subunits.UniRule annotation

    Protein-protein interaction databases

    STRINGi439855.EcSMS35_0740.

    Structurei

    3D structure databases

    ProteinModelPortaliB1LLG1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini9 – 244236ATP-graspUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the succinate/malate CoA ligase beta subunit family.UniRule annotation
    Contains 1 ATP-grasp domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0045.
    HOGENOMiHOG000007059.
    KOiK01903.
    OMAiKVVFMAS.
    OrthoDBiEOG644ZT0.

    Family and domain databases

    Gene3Di3.30.1490.20. 1 hit.
    3.30.470.20. 1 hit.
    3.40.50.261. 1 hit.
    HAMAPiMF_00558. Succ_CoA_beta.
    InterProiIPR011761. ATP-grasp.
    IPR013650. ATP-grasp_succ-CoA_synth-type.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR005811. CoA_ligase.
    IPR017866. Succ-CoA_synthase_bsu_CS.
    IPR005809. Succ_CoA_synthase_bsu.
    IPR016102. Succinyl-CoA_synth-like.
    [Graphical view]
    PANTHERiPTHR11815. PTHR11815. 1 hit.
    PfamiPF08442. ATP-grasp_2. 1 hit.
    PF00549. Ligase_CoA. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001554. SucCS_beta. 1 hit.
    SUPFAMiSSF52210. SSF52210. 1 hit.
    TIGRFAMsiTIGR01016. sucCoAbeta. 1 hit.
    PROSITEiPS50975. ATP_GRASP. 1 hit.
    PS01217. SUCCINYL_COA_LIG_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B1LLG1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNLHEYQAKQ LFARYGLPAP VGYACTTPRE AEEAASKIGA GPWVVKCQVH    50
    AGGRGKAGGV KVVNSKEDIR AFAENWLGKR LVTYQTDANG QPVNQILVEA 100
    ATDIAKELYL GAVVDRSSRR VVFMASTEGG VEIEKVAEET PHLIHKVALD 150
    PLTGPMPYQG RELAFKLGLE GKLVQQFTKI FMGLATIFLE RDLALIEINP 200
    LVITKQGDLI CLDGKLGADG NALFRQPDLR EMRDQSQEDP REAQAAQWEL 250
    NYVALDGNIG CMVNGAGLAM GTMDIVKLHG GEPANFLDVG GGATKERVTE 300
    AFKIILSDDK VKAVLVNIFG GIVRCDLIAD GIIGAVAEVG VNVPVVVRLE 350
    GNNAELGAKK LADSGLNIIA AKGLTDAAQQ VVAAVEGK 388
    Length:388
    Mass (Da):41,393
    Last modified:April 29, 2008 - v1
    Checksum:i09C429EC97A823CF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000970 Genomic DNA. Translation: ACB19410.1.
    RefSeqiYP_001742828.1. NC_010498.1.

    Genome annotation databases

    EnsemblBacteriaiACB19410; ACB19410; EcSMS35_0740.
    GeneIDi6145198.
    KEGGiecm:EcSMS35_0740.
    PATRICi18430317. VBIEscCol6161_0902.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000970 Genomic DNA. Translation: ACB19410.1 .
    RefSeqi YP_001742828.1. NC_010498.1.

    3D structure databases

    ProteinModelPortali B1LLG1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 439855.EcSMS35_0740.

    Proteomic databases

    PRIDEi B1LLG1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACB19410 ; ACB19410 ; EcSMS35_0740 .
    GeneIDi 6145198.
    KEGGi ecm:EcSMS35_0740.
    PATRICi 18430317. VBIEscCol6161_0902.

    Phylogenomic databases

    eggNOGi COG0045.
    HOGENOMi HOG000007059.
    KOi K01903.
    OMAi KVVFMAS.
    OrthoDBi EOG644ZT0.

    Enzyme and pathway databases

    UniPathwayi UPA00223 ; UER00999 .
    BioCyci ECOL439855:GHHB-738-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1490.20. 1 hit.
    3.30.470.20. 1 hit.
    3.40.50.261. 1 hit.
    HAMAPi MF_00558. Succ_CoA_beta.
    InterProi IPR011761. ATP-grasp.
    IPR013650. ATP-grasp_succ-CoA_synth-type.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR005811. CoA_ligase.
    IPR017866. Succ-CoA_synthase_bsu_CS.
    IPR005809. Succ_CoA_synthase_bsu.
    IPR016102. Succinyl-CoA_synth-like.
    [Graphical view ]
    PANTHERi PTHR11815. PTHR11815. 1 hit.
    Pfami PF08442. ATP-grasp_2. 1 hit.
    PF00549. Ligase_CoA. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001554. SucCS_beta. 1 hit.
    SUPFAMi SSF52210. SSF52210. 1 hit.
    TIGRFAMsi TIGR01016. sucCoAbeta. 1 hit.
    PROSITEi PS50975. ATP_GRASP. 1 hit.
    PS01217. SUCCINYL_COA_LIG_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Insights into the environmental resistance gene pool from the genome sequence of the multidrug-resistant environmental isolate Escherichia coli SMS-3-5."
      Fricke W.F., Wright M.S., Lindell A.H., Harkins D.M., Baker-Austin C., Ravel J., Stepanauskas R.
      J. Bacteriol. 190:6779-6794(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SMS-3-5 / SECEC.

    Entry informationi

    Entry nameiSUCC_ECOSM
    AccessioniPrimary (citable) accession number: B1LLG1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: April 29, 2008
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3