B1LJC7 (XYLA_ECOSM) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 31.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Xylose isomerase EC=5.3.1.5 | ||||
| Gene names |
| ||||
| Organism | Escherichia coli (strain SMS-3-5 / SECEC) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 439855 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia |
Protein attributes
| Sequence length | 440 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | D-xylose = D-xylulose. HAMAP MF_00455 |
| Cofactor | Binds 2 magnesium ions per subunit By similarity. HAMAP MF_00455 |
| Subunit structure | Homotetramer By similarity. HAMAP MF_00455 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00455. |
| Sequence similarities | Belongs to the xylose isomerase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Carbohydrate metabolism Pentose shunt Xylose metabolism |
| Cellular component | Cytoplasm |
| Ligand | Magnesium Metal-binding |
| Molecular function | Isomerase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | D-xylose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW pentose-phosphate shuntInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW xylose isomerase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 440 | 440 | Xylose isomerase HAMAP MF_00455 | PRO_1000200290 | |||||
Sites | |||||||||
| Active site | 101 | 1 | By similarity | ||||||
| Active site | 104 | 1 | By similarity | ||||||
| Metal binding | 232 | 1 | Magnesium 1 By similarity | ||||||
| Metal binding | 268 | 1 | Magnesium 1 By similarity | ||||||
| Metal binding | 268 | 1 | Magnesium 2 By similarity | ||||||
| Metal binding | 271 | 1 | Magnesium 2 By similarity | ||||||
| Metal binding | 296 | 1 | Magnesium 1 By similarity | ||||||
| Metal binding | 307 | 1 | Magnesium 2 By similarity | ||||||
| Metal binding | 309 | 1 | Magnesium 2 By similarity | ||||||
| Metal binding | 339 | 1 | Magnesium 1 By similarity | ||||||
Sequences
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References
| [1] | "Insights into the environmental resistance gene pool from the genome sequence of the multidrug-resistant environmental isolate Escherichia coli SMS-3-5." Fricke W.F., Wright M.S., Lindell A.H., Harkins D.M., Baker-Austin C., Ravel J., Stepanauskas R. J. Bacteriol. 190:6779-6794(2008) [PubMed: 18708504] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SMS-3-5 / SECEC. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000970 Genomic DNA. Translation: ACB17239.1. |
| RefSeq | YP_001745853.1. NC_010498.1. |
3D structure databases | |
| ProteinModelPortal | B1LJC7. |
| SMR | B1LJC7. Positions 2-439. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | B1LJC7. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBESCT00000063538; EBESCP00000061180; EBESCG00000062585. |
| GeneID | 6145005. |
| GenomeReviews | Gene locus EcSMS35_3888 in contig CP000970_GR. |
| KEGG | ecm:EcSMS35_3888. |
| PATRIC | 18436695. VBIEscCol6161_4030. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| GeneTree | EBGT00050000011705. |
| HOGENOM | HBG297199. |
| OMA | LLGWDTD. |
| ProtClustDB | PRK05474. |
Enzyme and pathway databases | |
| BioCyc | ECOL439855:ECSMS35_3888-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00455. Xylose_isom_A. [Tree] |
| InterPro | IPR013022. Xyl_isomerase-like_TIM-brl. IPR012307. Xyl_isomerase_TIM-brl. IPR013452. Xylose_isom_bac. IPR001998. Xylose_isomerase. [Graphical view] |
| Gene3D | G3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit. |
| KO | K01805. |
| Pfam | PF01261. AP_endonuc_2. 1 hit. [Graphical view] |
| PRINTS | PR00688. XYLOSISMRASE. |
| SUPFAM | SSF51658. Xyl_isomerase-like_TIM-brl. 1 hit. |
| TIGRFAMs | TIGR02630. Xylose_isom_A. 1 hit. |
| PROSITE | PS51415. XYLOSE_ISOMERASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | XYLA_ECOSM | ||||||||
| Accession | Primary (citable) accession number: B1LJC7 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

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