B1LFY2 (B1LFY2_ECOSM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrofolate reductase EMBL ACB16637.1
EC=1.5.1.3 EMBL ACB16637.1

Gene names

Name:	folA EMBL ACB16637.1
Ordered Locus Names:	EcSMS35_0050

Organism

Escherichia coli (strain SMS-3-5 / SECEC) [Complete proteome] [HAMAP] EMBL ACB16637.1

Taxonomic identifier

439855 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	196 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL ACB16637.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1LFY2 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: F8D7ACFEAF3E0D91	FASTA	196	22,300
	10 20 30 40 50 60 MDSPAEYKIF LNIILAPVDD GLRFTYSGDN FFYREISMIS LIAALAVDRV IGMENAMPWN 70 80 90 100 110 120 LPADLAWFKR NTLNKPVIMG RHTWESIGRP LPGRKNIILS SQPGTDDRVT WVKSVDEAIA 130 140 150 160 170 180 ACGDVPEIMV IGGGRVYEQF LPKAQKLYLT HIDAEVEGDT HFPDYEPDDW ESVFSEFHDA 190 DAQNSHSYCF EILERR

References

[1]

"Insights into the environmental resistance gene pool from the genome sequence of the multidrug-resistant environmental isolate Escherichia coli SMS-3-5." Fricke W.F., Wright M.S., Lindell A.H., Harkins D.M., Baker-Austin C., Ravel J., Stepanauskas R. J. Bacteriol. 190:6779-6794(2008) [PubMed: 18708504] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000970 Genomic DNA. Translation: ACB16637.1.
RefSeq	YP_001742167.1. NC_010498.1.
3D structure databases
ProteinModelPortal	B1LFY2.
SMR	B1LFY2. Positions 38-196.
ModBase	Search...
Protein-protein interaction databases
STRING	B1LFY2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000063083; EBESCP00000060725; EBESCG00000062130.
GeneID	6144196.
GenomeReviews	Gene locus EcSMS35_0050 in contig CP000970_GR.
KEGG	ecm:EcSMS35_0050.
PATRIC	18428928. VBIEscCol6161_0225.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000010807.
HOGENOM	HBG665708.
OMA	PTRFVVY.
ProtClustDB	PRK10769.
Family and domain databases
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR017925. DHFR_CS. IPR001796. DHFR_dom. [Graphical view]
Gene3D	G3DSA:3.40.430.10. G3DSA:3.40.430.10. 1 hit.
KO	K00287.
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PIRSF	PIRSF000194. DHFR. 1 hit.
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS00075. DHFR_1. 1 hit. PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B1LFY2_ECOSM

Accession

Primary (citable) accession number: B1LFY2

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)