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Reviewed, UniProtKB/Swiss-Prot B1LDV3 (MSRB_ECOSM)

Last modified November 3, 2009. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Peptide methionine sulfoxide reductase msrB
    EC=1.8.4.12
Alternative name(s):
    Peptide-methionine (R)-S-oxide reductase
Gene names
Name: msrB
Ordered Locus Names: EcSMS35_1413
OrganismEscherichia coli (strain SMS-3-5 / SECEC) [Complete proteome] [HAMAP]
Taxonomic identifier439855 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length137 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400

Cofactor

Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity.

Sequence similarities

Belongs to the msrB Met sulfoxide reductase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 137137Peptide methionine sulfoxide reductase msrB HAMAP MF_01400
PRO_1000145371

Sites

Active site1181Nucleophile By similarity
Metal binding461Zinc By similarity
Metal binding491Zinc By similarity
Metal binding951Zinc By similarity
Metal binding981Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
B1LDV3-1 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 7B9B783DBEBE0F71

FASTA13715,451
        10         20         30         40         50         60 
MANKPSAEEL KKNLSEMQFY VTQNHGTEPP FTGRLLHNKR DGVYHCLICD APLFHSQTKY 

        70         80         90        100        110        120 
DSGCGWPSFY EPVSEESIRY IKDLSHGMQR IEIRCGNCDA HLGHVFPDGP QPTGERYCVN 

       130 
SASLRFTDGE NGEEING 

« Hide

References

[1]"Insights into the environmental resistance gene pool from the genome sequence of the multidrug-resistant environmental isolate Escherichia coli SMS-3-5."
Fricke W.F., Wright M.S., Lindell A.H., Harkins D.M., Baker-Austin C., Ravel J., Stepanauskas R.
J. Bacteriol. 190:6779-6794(2008) [PubMed: 18708504] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000970 Genomic DNA. Translation: ACB16336.1.
RefSeqYP_001743471.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID6143783.
GenomeReviewsGene locus EcSMS35_1413 in contig CP000970_GR.
KEGGecm:EcSMS35_1413.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAFTGRYWD.

Family and domain databases

HAMAPMF_01400.
[Tree]
InterProIPR002579. Methionine_sulphoxide_MsrB.
[Graphical view]
Gene3DG3DSA:2.170.150.20. MsrB. 1 hit.
PfamPF01641. SelR. 1 hit.
[Graphical view]
ProDomPD004057. DUF25. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR00357. MsrB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMSRB_ECOSM
AccessionPrimary (citable) accession number: B1LDV3
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: November 3, 2009
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents