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B1L7A5 (IF5A_KORCO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Translation initiation factor 5A
Alternative name(s):
Hypusine-containing protein
eIF-5A
Gene names
Name:eIF5A
Ordered Locus Names:Kcr_1589
OrganismKorarchaeum cryptofilum (strain OPF8) [Reference proteome] [HAMAP]
Taxonomic identifier374847 [NCBI]
Taxonomic lineageArchaeaKorarchaeotaCandidatus Korarchaeum

Protein attributes

Sequence length134 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Functions by promoting the formation of the first peptide bond By similarity. HAMAP-Rule MF_00085

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00085.

Sequence similarities

Belongs to the eIF-5A family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 134134Translation initiation factor 5A HAMAP-Rule MF_00085
PRO_1000093008

Amino acid modifications

Modified residue361Hypusine By similarity

Sequences

Sequence LengthMass (Da)Tools
B1L7A5 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 8B3147BFBD2B2AAD

FASTA13414,821
        10         20         30         40         50         60 
MSVTRGSAGD LRKGSYVILD DEPCEVLEVS KSKPGKHGSA KVRVEARGIF DGARRSKIFP 

        70         80         90        100        110        120 
ADALVEIPIV DKKTAQVINV YGNVVQLMDL ETYETFELPL PEDPELASRL KSGIEVEYWE 

       130 
SMGKRKIVRT RGGV 

« Hide

References

[1]"A korarchaeal genome reveals new insights into the evolution of the Archaea."
Elkins J.G., Podar M., Graham D.E., Makarova K.S., Wolf Y., Randau L., Hedlund B.P., Brochier-Armanet C., Kunin V., Anderson I., Lapidus A., Goltsman E., Barry K., Koonin E.V., Hugenholtz P., Kyrpides N., Wanner G., Richardson P., Keller M., Stetter K.O.
Proc. Natl. Acad. Sci. U.S.A. 105:8102-8107(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: OPF8.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000968 Genomic DNA. Translation: ACB08334.1.
RefSeqYP_001738017.1. NC_010482.1.

3D structure databases

ProteinModelPortalB1L7A5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING374847.Kcr_1589.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACB08334; ACB08334; Kcr_1589.
GeneID6094865.
KEGGkcr:Kcr_1589.

Phylogenomic databases

eggNOGCOG0231.
HOGENOMHOG000106269.
KOK03263.
OMAIEKHVGQ.

Enzyme and pathway databases

BioCycKCRY374847:GH12-1630-MONOMER.

Family and domain databases

Gene3D2.30.30.30. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00085. eIF_5A.
InterProIPR012340. NA-bd_OB-fold.
IPR014722. Rib_L2_dom2.
IPR019769. Trans_elong_IF5A_hypusine_site.
IPR001884. Transl_elong_IF5A.
IPR022847. Transl_elong_IF5A_arc.
IPR020189. Transl_elong_IF5A_C.
IPR013185. Transl_elong_KOW-like.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PANTHERPTHR11673. PTHR11673. 1 hit.
PTHR11673:SF1. PTHR11673:SF1. 1 hit.
PfamPF08207. EFP_N. 1 hit.
PF01287. eIF-5a. 1 hit.
[Graphical view]
PIRSFPIRSF003025. eIF5A. 1 hit.
SUPFAMSSF50104. SSF50104. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00037. eIF_5A. 1 hit.
PROSITEPS00302. IF5A_HYPUSINE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIF5A_KORCO
AccessionPrimary (citable) accession number: B1L7A5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 29, 2008
Last modified: February 19, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries