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B1L7A5

- IF5A_KORCO

UniProt

B1L7A5 - IF5A_KORCO

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Protein
Translation initiation factor 5A
Gene
eIF5A, Kcr_1589
Organism
Korarchaeum cryptofilum (strain OPF8)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Functions by promoting the formation of the first peptide bond By similarity.UniRule annotation

GO - Molecular functioni

  1. ribosome binding Source: InterPro
  2. translation elongation factor activity Source: InterPro
  3. translation initiation factor activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. peptidyl-lysine modification to peptidyl-hypusine Source: InterPro
  2. positive regulation of translational elongation Source: InterPro
  3. positive regulation of translational termination Source: InterPro
  4. translational frameshifting Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciKCRY374847:GH12-1630-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor 5A
Alternative name(s):
Hypusine-containing protein
eIF-5A
Gene namesi
Name:eIF5A
Ordered Locus Names:Kcr_1589
OrganismiKorarchaeum cryptofilum (strain OPF8)
Taxonomic identifieri374847 [NCBI]
Taxonomic lineageiArchaeaKorarchaeotaCandidatus Korarchaeum
ProteomesiUP000001686: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 134134Translation initiation factor 5AUniRule annotation
PRO_1000093008Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei36 – 361Hypusine By similarity

Keywords - PTMi

Hypusine

Interactioni

Protein-protein interaction databases

STRINGi374847.Kcr_1589.

Structurei

3D structure databases

ProteinModelPortaliB1L7A5.

Family & Domainsi

Sequence similaritiesi

Belongs to the eIF-5A family.

Phylogenomic databases

eggNOGiCOG0231.
HOGENOMiHOG000106269.
KOiK03263.
OMAiAMGKMKI.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
2.40.50.140. 1 hit.
HAMAPiMF_00085. eIF_5A.
InterProiIPR012340. NA-bd_OB-fold.
IPR014722. Rib_L2_dom2.
IPR019769. Trans_elong_IF5A_hypusine_site.
IPR001884. Transl_elong_IF5A.
IPR022847. Transl_elong_IF5A_arc.
IPR020189. Transl_elong_IF5A_C.
IPR013185. Transl_elong_KOW-like.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PANTHERiPTHR11673. PTHR11673. 1 hit.
PfamiPF08207. EFP_N. 1 hit.
PF01287. eIF-5a. 1 hit.
[Graphical view]
PIRSFiPIRSF003025. eIF5A. 1 hit.
SUPFAMiSSF50104. SSF50104. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00037. eIF_5A. 1 hit.
PROSITEiPS00302. IF5A_HYPUSINE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1L7A5-1 [UniParc]FASTAAdd to Basket

« Hide

MSVTRGSAGD LRKGSYVILD DEPCEVLEVS KSKPGKHGSA KVRVEARGIF    50
DGARRSKIFP ADALVEIPIV DKKTAQVINV YGNVVQLMDL ETYETFELPL 100
PEDPELASRL KSGIEVEYWE SMGKRKIVRT RGGV 134
Length:134
Mass (Da):14,821
Last modified:April 29, 2008 - v1
Checksum:i8B3147BFBD2B2AAD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000968 Genomic DNA. Translation: ACB08334.1.
RefSeqiYP_001738017.1. NC_010482.1.

Genome annotation databases

EnsemblBacteriaiACB08334; ACB08334; Kcr_1589.
GeneIDi6094865.
KEGGikcr:Kcr_1589.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000968 Genomic DNA. Translation: ACB08334.1 .
RefSeqi YP_001738017.1. NC_010482.1.

3D structure databases

ProteinModelPortali B1L7A5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 374847.Kcr_1589.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACB08334 ; ACB08334 ; Kcr_1589 .
GeneIDi 6094865.
KEGGi kcr:Kcr_1589.

Phylogenomic databases

eggNOGi COG0231.
HOGENOMi HOG000106269.
KOi K03263.
OMAi AMGKMKI.

Enzyme and pathway databases

BioCyci KCRY374847:GH12-1630-MONOMER.

Family and domain databases

Gene3Di 2.30.30.30. 1 hit.
2.40.50.140. 1 hit.
HAMAPi MF_00085. eIF_5A.
InterProi IPR012340. NA-bd_OB-fold.
IPR014722. Rib_L2_dom2.
IPR019769. Trans_elong_IF5A_hypusine_site.
IPR001884. Transl_elong_IF5A.
IPR022847. Transl_elong_IF5A_arc.
IPR020189. Transl_elong_IF5A_C.
IPR013185. Transl_elong_KOW-like.
IPR008991. Translation_prot_SH3-like.
[Graphical view ]
PANTHERi PTHR11673. PTHR11673. 1 hit.
Pfami PF08207. EFP_N. 1 hit.
PF01287. eIF-5a. 1 hit.
[Graphical view ]
PIRSFi PIRSF003025. eIF5A. 1 hit.
SUPFAMi SSF50104. SSF50104. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00037. eIF_5A. 1 hit.
PROSITEi PS00302. IF5A_HYPUSINE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: OPF8.

Entry informationi

Entry nameiIF5A_KORCO
AccessioniPrimary (citable) accession number: B1L7A5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 29, 2008
Last modified: July 9, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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