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Protein

Glyoxylate reductase

Gene

gyaR

Organism
Korarchaeum cryptofilum (strain OPF8)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Glycolate + NAD+ = glyoxylate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei238UniRule annotation1
Active sitei267UniRule annotation1
Active sitei286Proton donorUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi155 – 158NADPUniRule annotation4
Nucleotide bindingi236 – 238NADPUniRule annotation3
Nucleotide bindingi286 – 288NADPUniRule annotation3

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Enzyme and pathway databases

BioCyciCKOR374847:G1GBF-1634-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glyoxylate reductaseUniRule annotation (EC:1.1.1.26UniRule annotation)
Gene namesi
Name:gyaRUniRule annotation
Ordered Locus Names:Kcr_1548
OrganismiKorarchaeum cryptofilum (strain OPF8)
Taxonomic identifieri374847 [NCBI]
Taxonomic lineageiArchaeaCandidatus KorarchaeotaCandidatus Korarchaeum
Proteomesi

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003484151 – 332Glyoxylate reductaseAdd BLAST332

Proteomic databases

PRIDEiB1L765

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi374847.Kcr_1548

Structurei

3D structure databases

ProteinModelPortaliB1L765
SMRiB1L765
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01755 Archaea
COG1052 LUCA
HOGENOMiHOG000136700
InParanoidiB1L765
KOiK00015
OMAiKWIAHNG
OrthoDBiPOG093Z0DW1

Family and domain databases

HAMAPiMF_00776 GyaR, 1 hit
InterProiView protein in InterPro
IPR006139 D-isomer_2_OHA_DH_cat_dom
IPR029753 D-isomer_DH_CS
IPR029752 D-isomer_DH_CS1
IPR006140 D-isomer_DH_NAD-bd
IPR023519 Glyoxylate_reductase_GyaR
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF00389 2-Hacid_dh, 1 hit
PF02826 2-Hacid_dh_C, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS00065 D_2_HYDROXYACID_DH_1, 1 hit
PS00670 D_2_HYDROXYACID_DH_2, 1 hit
PS00671 D_2_HYDROXYACID_DH_3, 1 hit

Sequencei

Sequence statusi: Complete.

B1L765-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPRVFVTRE IPERGLSKIE EHFELDLWKD EAPPSKKVII ERVKDCDALV
60 70 80 90 100
SLLTDPIDAE VFEAAPKLRI VAQYAVGYDN IDVKEATKRG IYVTNTPGVL
110 120 130 140 150
TETTADFAFA LLMAAARRVV EADRYVREGK WKVAWHPMMM LGYDVYGRTL
160 170 180 190 200
GIVGMGRIGA AVARRAKGFG MRILYYDSIR REDFEKELGV EYVPLEKLLE
210 220 230 240 250
ESDFVSLHVP LTEETYHMIG EEQLRRMKRT AILVNTSRGK VVDQKALYKA
260 270 280 290 300
LKEGWIAGAG LDVFEQEPIP PDDPLLKLEN VVLAPHAASA SHETRSRMAE
310 320 330
MVAENLIAFK RGEIPPNLVN QEVVKVRPPG FQ
Length:332
Mass (Da):37,477
Last modified:April 29, 2008 - v1
Checksum:i4A4A0FCA2D144207
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000968 Genomic DNA Translation: ACB08294.1
RefSeqiWP_012310191.1, NC_010482.1

Genome annotation databases

EnsemblBacteriaiACB08294; ACB08294; Kcr_1548
GeneIDi6094825
KEGGikcr:Kcr_1548

Similar proteinsi

Entry informationi

Entry nameiGYAR_KORCO
AccessioniPrimary (citable) accession number: B1L765
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: April 29, 2008
Last modified: March 28, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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