B1L4D7 (B1L4D7_KORCO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hydroxymethylglutaryl-CoA reductase, degradative EMBL ACB07316.1
EC=1.1.1.88 EMBL ACB07316.1

Gene names

Ordered Locus Names:

Kcr_0563

Organism

Korarchaeum cryptofilum (strain OPF8)

Taxonomic identifier

374847 [NCBI]

Taxonomic lineage

Archaea › Korarchaeota › Candidatus Korarchaeum

Protein attributes

Sequence length	423 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the HMG-CoA reductase family. RuleBase RU004268

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL ACB07316.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	coenzyme A metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase (NADPH) activity Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1L4D7 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: C937262DEDC9CB27	FASTA	423	45,907
	10 20 30 40 50 60 MRTSRISGFY NLPMDERLKI VREFAGLTDE EVEVLREGKL PREVADHMIE NVIGLYSLPF 70 80 90 100 110 120 AIATNFLING KDYLIPMVIE EPSVVAAASN AAKMARDSGG FEAEATDSIM ISQIQVVKVP 130 140 150 160 170 180 DLEEAIRRIM AEKDKLIAAA NEMDPLLTRL GGGARDLEVR VVGTEAGPML IVHLLVDTLD 190 200 210 220 230 240 AMGANTVNTM AEGLAPTIER LTGGKVYLRI ISNLADRRLA RAKAKFSKAA IGGEEVVEGI 250 260 270 280 290 300 MWAYRFAKHD PYRAATHNKG IMNGIIAVAL ATGQDTRALE AGAHSYAARS GKYTTLTNYW 310 320 330 340 350 360 VDDNGDLWGS IELPLAVGTV GGVVRVHPIA KIALKILGVE KARELAMIMA SVGLAQNFAA 370 380 390 400 410 420 LRALATEGIQ AGHMKLHARN IAMSVGASPS EIDEVVERMI RERKINVERA KQILEEMRSG KKA

References

[1]

"A korarchaeal genome reveals new insights into the evolution of the Archaea." Elkins J.G., Podar M., Graham D.E., Makarova K.S., Wolf Y., Randau L., Hedlund B.P., Brochier-Armanet C., Kunin V., Anderson I., Lapidus A., Goltsman E., Barry K., Koonin E.V., Hugenholtz P., Kyrpides N., Wanner G., Richardson P., Keller M., Stetter K.O. Proc. Natl. Acad. Sci. U.S.A. 105:8102-8107(2008) [PubMed: 18535141] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: OPF8.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000968 Genomic DNA. Translation: ACB07316.1.
RefSeq	YP_001736999.1. NC_010482.1.
3D structure databases
ProteinModelPortal	B1L4D7.
SMR	B1L4D7. Positions 3-419.
ModBase	Search...
Protein-protein interaction databases
STRING	B1L4D7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6093847.
GenomeReviews	Gene locus Kcr_0563 in contig CP000968_GR.
KEGG	kcr:Kcr_0563.
Phylogenomic databases
HOGENOM	HBG477902.
OMA	NNKGIMN.
Family and domain databases
InterPro	IPR002202. HMG_CoA_Rdtase. IPR004553. HMG_CoA_Rdtase_bac-typ. IPR023074. HMG_CoA_Rdtase_cat. IPR009023. HMG_CoA_Rdtase_NAD(P)-bd. IPR009029. HMG_CoA_Rdtase_sub-bd. [Graphical view]
Gene3D	G3DSA:3.30.70.420. G3DSA:3.30.70.420. 1 hit. G3DSA:3.90.770.10. HMG-CoA_red. 2 hits.
KO	K00054.
PANTHER	PTHR10572. HMG-CoA_red. 1 hit.
Pfam	PF00368. HMG-CoA_red. 1 hit. [Graphical view]
SUPFAM	SSF55035. HMG_CoA_NAD_bind. 1 hit. SSF56542. HMG_CoA_sub_bind. 1 hit.
TIGRFAMs	TIGR00532. HMG_CoA_R_NAD. 1 hit.
PROSITE	PS50065. HMG_COA_REDUCTASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B1L4D7_KORCO

Accession

Primary (citable) accession number: B1L4D7

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	November 16, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)