B1L3H9 (B1L3H9_KORCO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-dehydroquinate dehydratase HAMAP MF_00214
Short name=3-dehydroquinase HAMAP MF_00214
EC=4.2.1.10 HAMAP MF_00214

Alternative name(s):
Type I DHQase HAMAP MF_00214

Gene names

Name:	aroD HAMAP MF_00214
Ordered Locus Names:	Kcr_0248

Organism

Korarchaeum cryptofilum (strain OPF8)

Taxonomic identifier

374847 [NCBI]

Taxonomic lineage

Archaea › Korarchaeota › Candidatus Korarchaeum

Protein attributes

Sequence length	192 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	3-dehydroquinate = 3-dehydroshikimate + H2O. HAMAP MF_00214
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7. HAMAP MF_00214
Sequence similarities	Belongs to the type-I 3-dehydroquinase family. HAMAP MF_00214

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00214
Ligand	Schiff base HAMAP MF_00214
Molecular function	Lyase HAMAP MF_00214 EMBL ACB07008.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	3-dehydroquinate dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	90	1	Proton acceptor By similarity HAMAP MF_00214
	Active site	116	1	Schiff-base intermediate with substrate By similarity HAMAP MF_00214

Sequences

	Sequence		Length	Mass (Da)
	B1L3H9 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 3253983708E7EE47	FASTA	192	21,397
	10 20 30 40 50 60 MERAFKMGAD LVELRVDLIW DELPSADSLS SLISGFNDRV IITYRSRAHG GKGESQDVEW 70 80 90 100 110 120 LRSVSKICGY VDVEYENSRI GIGNAIFSWH DPSGTPSYEE LLSISEELLS LGGIAKIVTY 130 140 150 160 170 180 ARDEREAYRV LSLYKLEHRR RLVAFSMGER GSFSRRLSAA LGSPLIYSYL GKAAAEGQIS 190 LDEAVLLKEL LS

References

[1]

"A korarchaeal genome reveals new insights into the evolution of the Archaea." Elkins J.G., Podar M., Graham D.E., Makarova K.S., Wolf Y., Randau L., Hedlund B.P., Brochier-Armanet C., Kunin V., Anderson I., Lapidus A., Goltsman E., Barry K., Koonin E.V., Hugenholtz P., Kyrpides N., Wanner G., Richardson P., Keller M., Stetter K.O. Proc. Natl. Acad. Sci. U.S.A. 105:8102-8107(2008) [PubMed: 18535141] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: OPF8.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000968 Genomic DNA. Translation: ACB07008.1.
RefSeq	YP_001736691.1. NC_010482.1.
3D structure databases
ProteinModelPortal	B1L3H9.
ModBase	Search...
Protein-protein interaction databases
STRING	B1L3H9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6093537.
GenomeReviews	Gene locus Kcr_0248 in contig CP000968_GR.
KEGG	kcr:Kcr_0248.
Phylogenomic databases
HOGENOM	HBG732926.
OMA	PICTSIM.
PhylomeDB	B1L3H9.
Family and domain databases
HAMAP	MF_00214. AroD. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001381. DHquinase_I. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K03785.
Pfam	PF01487. DHquinase_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B1L3H9_KORCO

Accession

Primary (citable) accession number: B1L3H9

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)