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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Korarchaeum cryptofilum (strain OPF8)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciKCRY374847:GH12-218-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Kcr_0213
OrganismiKorarchaeum cryptofilum (strain OPF8)
Taxonomic identifieri374847 [NCBI]
Taxonomic lineageiArchaeaKorarchaeotaCandidatus Korarchaeum
ProteomesiUP000001686: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 632632Arginine--tRNA ligasePRO_1000095374Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi374847.Kcr_0213.

Structurei

3D structure databases

ProteinModelPortaliB1L3E4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi129 – 13911"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247213.
InParanoidiB1L3E4.
KOiK01887.
OMAiVGFGTMM.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.

Sequencei

Sequence statusi: Complete.

B1L3E4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKDPLGAVK STFAEEVNRV LRDLGSATRF SPIQVSRVRK DYASYGLPVG
60 70 80 90 100
FKVAKDLNLD PERAAKTVLD RIDMSRIAYS SDAYAESGYL NLRIDKARFF
110 120 130 140 150
RDILKLASSE ELGRGERKGV VGMVEHTSAN PVHPLHVGSG RNAVIGDSFS
160 170 180 190 200
RILNFLGWDV RRHYLVNDCN LQVAILAAGR SKVRDLIPKG KVDHWFGLIY
210 220 230 240 250
AISNAFLEIW RIKNGFNSES KIEEWSEVVE RIGRMEPELL RIGELSEEEV
260 270 280 290 300
MSLLREYQRK EGGSVQMFRE ITESVLRGFV ETLERMGITY DSFDRESELI
310 320 330 340 350
WDGWVDRAIE KLESSGYLKR EGKAAYVDLW EAAKGDENVR KVFELSEDDI
360 370 380 390 400
SKLEREGKLG EVIPRKFYLT RSDGTWLYTG TDVAYSLYKF DGLGVSFCYN
410 420 430 440 450
VIASEQNMEQ KGVRACLALM GHDPGKLIHL SYEMVNLVGA AMSGRRGLYI
460 470 480 490 500
TLDEVLDEAK RRVEAILKER GIYDEEICEK VAIGALKYGL ISVSPNKVVQ
510 520 530 540 550
FRWERVLNLE ENSGPFIQYA YTRALNIIKK AQGVPEDFDP NELKSDAEIT
560 570 580 590 600
IVQMISEFPE RVWSAFNLMR PDIIASYANE LASQFNKFYE DHPVLSAARP
610 620 630
EERAARLNLV NAVKGTLGLA MDLIGIPRLE RM
Length:632
Mass (Da):71,667
Last modified:April 29, 2008 - v1
Checksum:i751ACAF493D4691C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000968 Genomic DNA. Translation: ACB06973.1.
RefSeqiYP_001736656.1. NC_010482.1.

Genome annotation databases

EnsemblBacteriaiACB06973; ACB06973; Kcr_0213.
GeneIDi6093502.
KEGGikcr:Kcr_0213.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000968 Genomic DNA. Translation: ACB06973.1.
RefSeqiYP_001736656.1. NC_010482.1.

3D structure databases

ProteinModelPortaliB1L3E4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi374847.Kcr_0213.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACB06973; ACB06973; Kcr_0213.
GeneIDi6093502.
KEGGikcr:Kcr_0213.

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247213.
InParanoidiB1L3E4.
KOiK01887.
OMAiVGFGTMM.

Enzyme and pathway databases

BioCyciKCRY374847:GH12-218-MONOMER.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: OPF8.

Entry informationi

Entry nameiSYR_KORCO
AccessioniPrimary (citable) accession number: B1L3E4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 29, 2008
Last modified: January 7, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.