B1L394 (B1L394_KORCO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Argininosuccinate lyase HAMAP MF_00006
Short name=ASAL HAMAP MF_00006
EC=4.3.2.1 HAMAP MF_00006

Alternative name(s):
Arginosuccinase HAMAP MF_00006

Gene names

Name:	argH HAMAP MF_00006
Ordered Locus Names:	Kcr_0163

Organism

Korarchaeum cryptofilum (strain OPF8)

Taxonomic identifier

374847 [NCBI]

Taxonomic lineage

Archaea › Korarchaeota › Candidatus Korarchaeum

Protein attributes

Sequence length	455 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. HAMAP MF_00006
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3. HAMAP MF_00006
Subcellular location	Cytoplasm By similarity HAMAP MF_00006.
Sequence similarities	Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. HAMAP MF_00006

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis HAMAP MF_00006
Cellular component	Cytoplasm HAMAP MF_00006
Molecular function	Lyase HAMAP MF_00006 EMBL ACB06923.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process via ornithine Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	argininosuccinate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1L394 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: B09712D1A7162178	FASTA	455	51,140
	10 20 30 40 50 60 MGDQSDWLTE FISSIDSDRR IFRATVLTAL AHQIHLFESG LLPKEAALTI SLLLEALDKE 70 80 90 100 110 120 DEILSRDFED VHEALESWVI ERAGNLGGWL AYGKSRNDQV ATALRYVTIR ELISLLWEIN 130 140 150 160 170 180 RLRDSLIDAA LMNLEKRIPA FTHLQPAQPS TVSHYLLSIE YELFHHYRSI WHVMREIVDL 190 200 210 220 230 240 CPLGSGPAAG SSVPMDRGRL ADLLGFSGVE SNTLLATGSR SFETIVLGIL SSLMVVLSRV 250 260 270 280 290 300 CEDLIIWSTP NFGLVELPDD HVSTSSIMPQ KRNPVTLEVI RAKAGEVMGC HFTVLSVMKG 310 320 330 340 350 360 LPSGYNLDIQ ETNEPFLRAI DTTKGSLKVL SDLIRRSRFR ESESEITLAQ FIAEELVRRR 370 380 390 400 410 420 GISYREAHSI LASTLRESGW DLRKAVHSLG LELPSSYEVK VRGGPNPESL KGELEARRRL 430 440 450 LRDDISRLVE YEAEKMESEK RLIDLARKLA GRSPQ

References

[1]

"A korarchaeal genome reveals new insights into the evolution of the Archaea." Elkins J.G., Podar M., Graham D.E., Makarova K.S., Wolf Y., Randau L., Hedlund B.P., Brochier-Armanet C., Kunin V., Anderson I., Lapidus A., Goltsman E., Barry K., Koonin E.V., Hugenholtz P., Kyrpides N., Wanner G., Richardson P., Keller M., Stetter K.O. Proc. Natl. Acad. Sci. U.S.A. 105:8102-8107(2008) [PubMed: 18535141] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: OPF8.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000968 Genomic DNA. Translation: ACB06923.1.
RefSeq	YP_001736606.1. NC_010482.1.
3D structure databases
ProteinModelPortal	B1L394.
ModBase	Search...
Protein-protein interaction databases
STRING	B1L394.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6093452.
GenomeReviews	Gene locus Kcr_0163 in contig CP000968_GR.
KEGG	kcr:Kcr_0163.
Phylogenomic databases
HOGENOM	HBG539632.
OMA	EDIHTVI.
PhylomeDB	B1L394.
Family and domain databases
HAMAP	MF_00006. Arg_succ_lyase. [Tree]
InterPro	IPR009049. Argininosuccinate_lyase. IPR003031. D_crystallin. IPR000362. Fumarate_lyase. IPR008948. L-Aspartase-like. IPR022761. Lyase1_N. [Graphical view]
KO	K01755.
PANTHER	PTHR11444:SF3. argH. 1 hit.
Pfam	PF00206. Lyase_1. 1 hit. [Graphical view]
PRINTS	PR00145. ARGSUCLYASE. PR00149. FUMRATELYASE.
SUPFAM	SSF48557. L-Aspartase-like. 1 hit.
TIGRFAMs	TIGR00838. ArgH. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1L394_KORCO

Accession

Primary (citable) accession number: B1L394

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)