ID   3MGH_CLOBM              Reviewed;         203 AA.
AC   B1KZY0;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=CLK_0705;
OS   Clostridium botulinum (strain Loch Maree / Type A3).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=498214;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Loch Maree / Type A3;
RX   PubMed=18060065; DOI=10.1371/journal.pone.0001271;
RA   Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C.,
RA   Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S.;
RT   "Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4
RT   and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within
RT   plasmids.";
RL   PLoS ONE 2:E1271-E1271(2007).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR   EMBL; CP000962; ACA54217.1; -; Genomic_DNA.
DR   RefSeq; WP_012342349.1; NC_010520.1.
DR   AlphaFoldDB; B1KZY0; -.
DR   SMR; B1KZY0; -.
DR   KEGG; cbl:CLK_0705; -.
DR   HOGENOM; CLU_060471_0_2_9; -.
DR   Proteomes; UP000000722; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; Methylpurine-DNA glycosylase (MPG); 1.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   NCBIfam; TIGR00567; 3mg; 1.
DR   PANTHER; PTHR10429; DNA-3-METHYLADENINE GLYCOSYLASE; 1.
DR   PANTHER; PTHR10429:SF0; DNA-3-METHYLADENINE GLYCOSYLASE; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; FMT C-terminal domain-like; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase.
FT   CHAIN           1..203
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_1000127759"
SQ   SEQUENCE   203 AA;  23547 MW;  A653FCA5D7328DDB CRC64;
     MRLTRDFYAK DARVLAKELL GKVLVREVDG IKLKGKIVET EAYIGAIDKA SHAYGGRRTK
     RTEPLYGKPG IAYVYFIYGK YFCFNIISKT EGEAEGVLIR ALEPLENINL ISKLRFNKEF
     EELNNYQRKN ITSGPSKLCM AFNINRDNNW EDLCESSSLY VEDVLYNDFE IIETVRVGID
     YAEEARDFLW RYYIKDNAFV SVK
//