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Protein

Putative 3-methyladenine DNA glycosylase

Gene

CLK_0705

Organism
Clostridium botulinum (strain Loch Maree / Type A3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

DNA damage, DNA repair

Enzyme and pathway databases

BioCyciCBOT498214:GH05-1366-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative 3-methyladenine DNA glycosylaseUniRule annotation (EC:3.2.2.-UniRule annotation)
Gene namesi
Ordered Locus Names:CLK_0705
OrganismiClostridium botulinum (strain Loch Maree / Type A3)
Taxonomic identifieri498214 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000000722 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 203203Putative 3-methyladenine DNA glycosylasePRO_1000127759Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi498214.CLK_0705.

Structurei

3D structure databases

ProteinModelPortaliB1KZY0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DNA glycosylase MPG family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2094.
HOGENOMiHOG000224224.
KOiK03652.
OMAiEHISSQY.
OrthoDBiEOG6Q2SQ1.

Family and domain databases

Gene3Di3.10.300.10. 1 hit.
HAMAPiMF_00527. 3MGH.
InterProiIPR011034. Formyl_transferase_C-like.
IPR003180. PurDNA_glycsylse.
[Graphical view]
PANTHERiPTHR10429. PTHR10429. 1 hit.
PfamiPF02245. Pur_DNA_glyco. 1 hit.
[Graphical view]
SUPFAMiSSF50486. SSF50486. 1 hit.
TIGRFAMsiTIGR00567. 3mg. 1 hit.

Sequencei

Sequence statusi: Complete.

B1KZY0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLTRDFYAK DARVLAKELL GKVLVREVDG IKLKGKIVET EAYIGAIDKA
60 70 80 90 100
SHAYGGRRTK RTEPLYGKPG IAYVYFIYGK YFCFNIISKT EGEAEGVLIR
110 120 130 140 150
ALEPLENINL ISKLRFNKEF EELNNYQRKN ITSGPSKLCM AFNINRDNNW
160 170 180 190 200
EDLCESSSLY VEDVLYNDFE IIETVRVGID YAEEARDFLW RYYIKDNAFV

SVK
Length:203
Mass (Da):23,547
Last modified:April 29, 2008 - v1
Checksum:iA653FCA5D7328DDB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000962 Genomic DNA. Translation: ACA54217.1.
RefSeqiWP_012342349.1. NC_010520.1.
YP_001786652.1. NC_010520.1.

Genome annotation databases

EnsemblBacteriaiACA54217; ACA54217; CLK_0705.
KEGGicbl:CLK_0705.
PATRICi19388024. VBICloBot822_1625.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000962 Genomic DNA. Translation: ACA54217.1.
RefSeqiWP_012342349.1. NC_010520.1.
YP_001786652.1. NC_010520.1.

3D structure databases

ProteinModelPortaliB1KZY0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi498214.CLK_0705.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACA54217; ACA54217; CLK_0705.
KEGGicbl:CLK_0705.
PATRICi19388024. VBICloBot822_1625.

Phylogenomic databases

eggNOGiCOG2094.
HOGENOMiHOG000224224.
KOiK03652.
OMAiEHISSQY.
OrthoDBiEOG6Q2SQ1.

Enzyme and pathway databases

BioCyciCBOT498214:GH05-1366-MONOMER.

Family and domain databases

Gene3Di3.10.300.10. 1 hit.
HAMAPiMF_00527. 3MGH.
InterProiIPR011034. Formyl_transferase_C-like.
IPR003180. PurDNA_glycsylse.
[Graphical view]
PANTHERiPTHR10429. PTHR10429. 1 hit.
PfamiPF02245. Pur_DNA_glyco. 1 hit.
[Graphical view]
SUPFAMiSSF50486. SSF50486. 1 hit.
TIGRFAMsiTIGR00567. 3mg. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids."
    Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C., Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S.
    PLoS ONE 2:E1271-E1271(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Loch Maree / Type A3.

Entry informationi

Entry namei3MGH_CLOBM
AccessioniPrimary (citable) accession number: B1KZY0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: May 27, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.