B1KZY0 (3MGH_CLOBM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative 3-methyladenine DNA glycosylase
EC=3.2.2.-

Gene names

Ordered Locus Names:

CLK_0705

Organism

Clostridium botulinum (strain Loch Maree / Type A3) [Complete proteome] [HAMAP]

Taxonomic identifier

498214 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium › Clostridium botulinum › Clostridium botulinum A

Protein attributes

Sequence length	203 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the DNA glycosylase MPG family.

Ontologies

Keywords
Biological process	DNA damage DNA repair
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	base-excision repair Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro alkylbase DNA N-glycosylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 203	203	Putative 3-methyladenine DNA glycosylase HAMAP-Rule MF_00527		PRO_1000127759

Sequences

	Sequence		Length	Mass (Da)
	B1KZY0 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: A653FCA5D7328DDB	FASTA	203	23,547
	10 20 30 40 50 60 MRLTRDFYAK DARVLAKELL GKVLVREVDG IKLKGKIVET EAYIGAIDKA SHAYGGRRTK 70 80 90 100 110 120 RTEPLYGKPG IAYVYFIYGK YFCFNIISKT EGEAEGVLIR ALEPLENINL ISKLRFNKEF 130 140 150 160 170 180 EELNNYQRKN ITSGPSKLCM AFNINRDNNW EDLCESSSLY VEDVLYNDFE IIETVRVGID 190 200 YAEEARDFLW RYYIKDNAFV SVK

References

[1]

"Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids." Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C., Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S. PLoS ONE 2:E1271-E1271(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Loch Maree / Type A3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000962 Genomic DNA. Translation: ACA54217.1.
RefSeq	YP_001786652.1. NC_010520.1.
3D structure databases
ProteinModelPortal	B1KZY0.
ModBase	Search...
Protein-protein interaction databases
STRING	498214.CLK_0705.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACA54217; ACA54217; CLK_0705.
GeneID	6151712.
KEGG	cbl:CLK_0705.
PATRIC	19388024. VBICloBot822_1625.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2094.
HOGENOM	HOG000224224.
KO	K03652.
OMA	EHISSQY.
ProtClustDB	PRK00802.
Enzyme and pathway databases
BioCyc	CBOT498214:GH05-627-MONOMER.
Family and domain databases
Gene3D	3.10.300.10. 1 hit.
HAMAP	MF_00527. 3MGH.
InterPro	IPR011034. Formyl_transferase_C-like. IPR003180. PurDNA_glycsylse. [Graphical view]
PANTHER	PTHR10429. PTHR10429. 1 hit.
Pfam	PF02245. Pur_DNA_glyco. 1 hit. [Graphical view]
SUPFAM	SSF50486. FMT_C_like. 1 hit.
TIGRFAMs	TIGR00567. 3mg. 1 hit.
ProtoNet	Search...

Entry information

Entry name

3MGH_CLOBM

Accession

Primary (citable) accession number: B1KZY0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	April 29, 2008
Last modified:	May 1, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program