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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Clostridium botulinum (strain Loch Maree / Type A3)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:CLK_0517
OrganismiClostridium botulinum (strain Loch Maree / Type A3)
Taxonomic identifieri498214 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000000722 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000953531 – 563Arginine--tRNA ligaseAdd BLAST563

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB1KYT1
SMRiB1KYT1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi120 – 130"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247211
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
3.40.50.6201 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

B1KYT1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDYKNLVAER IKENTELEVD LIEKLIEIPP KKDMGDYAFP CFQLAKTFRK
60 70 80 90 100
APNLIAEELK EKINKEGFEK VVTVGPYLNF FVDKTVLIKD VLEKVLNEKE
110 120 130 140 150
KYGSSKVGEG KNVVVEYSSP NIAKPFHIGH LFTTAIGNAL YKILSFEGYN
160 170 180 190 200
CIGINHLGDW GTQFGKLISA YRRWVDEEAL EKDAIGELLR IYVKFHEEAE
210 220 230 240 250
KNPELEKEAR LNFKKLEDGS EEETELWNRF KDLSLKEFNK VYDMLGIKFD
260 270 280 290 300
SLAGESFYSD KMDAVVQEID DKGLLVDSNG AKVVMLDDYN MPPCMIKKSD
310 320 330 340 350
GATIYATRDL AAAMYRKKTY DFHKCIYVVG TPQALHFKQV FTTLKLMGHD
360 370 380 390 400
WADDCKHVGF GLVKLANKKL STRNGDVVFL EDLLNQSVEE TLKIINEKNP
410 420 430 440 450
NLKDKEGTAK KLGIGAVVFT YLKNNRERDI VFDWKEILSF DGETGPYVEY
460 470 480 490 500
SYARGKSILR KAGELTGEAD YSKLSSKEEF ELAKLLGGFN DAIMNAIDKL
510 520 530 540 550
EPAMVTRYVI EVAKAFNKFY NAHGILNAED NDVKLARVKL VEATCQVIKN
560
ALNLLGIDVV EEM
Length:563
Mass (Da):63,917
Last modified:April 29, 2008 - v1
Checksum:i1089717F4CA2B743
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000962 Genomic DNA Translation: ACA55304.1
RefSeqiWP_012343306.1, NC_010520.1

Genome annotation databases

EnsemblBacteriaiACA55304; ACA55304; CLK_0517
KEGGicbl:CLK_0517

Similar proteinsi

Entry informationi

Entry nameiSYR_CLOBM
AccessioniPrimary (citable) accession number: B1KYT1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 29, 2008
Last modified: January 31, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome