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Protein

16S rRNA (cytosine(967)-C(5))-methyltransferase

Gene

sun

Organism
Clostridium botulinum (strain Loch Maree / Type A3)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei283S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei310S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei328S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei381NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotationImported, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
16S rRNA (cytosine(967)-C(5))-methyltransferaseSAAS annotation (EC:2.1.1.176SAAS annotation)
Gene namesi
Name:sunImported
Ordered Locus Names:CLK_1889Imported
OrganismiClostridium botulinum (strain Loch Maree / Type A3)Imported
Taxonomic identifieri498214 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000000722 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliB1KX57.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini169 – 442SAM_MT_RSMB_NOPInterPro annotationAdd BLAST274

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000037300.
KOiK03500.
OMAiLRVNRQH.
OrthoDBiPOG091H02E2.

Family and domain databases

Gene3Di1.10.940.10. 1 hit.
InterProiView protein in InterPro
IPR001678. MeTrfase_RsmB/NOP2.
IPR006027. NusB_RsmB_TIM44.
IPR023267. RCMT.
IPR004573. rRNA_ssu_MeTfrase_B.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF01029. NusB. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF48013. SSF48013. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00563. rsmB. 1 hit.
PROSITEiView protein in PROSITE
PS51686. SAM_MT_RSMB_NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

B1KX57-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNAREVALD VLKAVLFEGA YSNIVLSKKL NKSNLKDNDK ALITEIVYGT
60 70 80 90 100
LKYKETLDII IQSYLRNPIK TMDKNIVNIL RITIYQIRYL DKIPSFAAVN
110 120 130 140 150
EAVEMSKKIS IKYSKLVNGV LRNYIRTYKN KKFYDHRNNL EKFSFMYSYP
160 170 180 190 200
KWLIKMFISQ YGIEIAEKIL KGLNERPNIT VRVNNLKIDY DEAFEKLGEY
210 220 230 240 250
GYNIEEGYIC PEAIQIIKGK NIEKNPLFIE GNITVQDESA MLVAPSMELD
260 270 280 290 300
EESIVLDLCS APGGKTTHIS EIMNNKSKVY AYDIHQNKLS LIEANAKRLG
310 320 330 340 350
IKNIETDVGD AAVFNKKLKE KAYRVVMDVP CSGLGIIRKK PEIKWTKNER
360 370 380 390 400
EIKNIIDIQR KIMNNGASYL KEGGILLYST CTLNKEENEE NINWFLKKHK
410 420 430 440
NFKIEPLYYG DVDNIIYHKE GFVSILPNDK MDGFFIAKLK KC
Length:442
Mass (Da):51,017
Last modified:April 29, 2008 - v1
Checksum:i87EB42485AA9F7FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000962 Genomic DNA. Translation: ACA53672.1.
RefSeqiWP_012341870.1. NC_010520.1.

Genome annotation databases

EnsemblBacteriaiACA53672; ACA53672; CLK_1889.
KEGGicbl:CLK_1889.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiB1KX57_CLOBM
AccessioniPrimary (citable) accession number: B1KX57
Entry historyiIntegrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: June 7, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported