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Protein
Submitted name:

Putative type I site-specific deoxyribonuclease, HsdR family subfamily

Gene

CLK_1539

Organism
Clostridium botulinum (strain Loch Maree / Type A3)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA binding Source: InterPro
  3. Type I site-specific deoxyribonuclease activity Source: InterPro

GO - Biological processi

  1. DNA restriction-modification system Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciCBOT498214:GH05-2195-MONOMER.

Protein family/group databases

REBASEi17443. CboA3ORF1538P.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative type I site-specific deoxyribonuclease, HsdR family subfamilyImported
Gene namesi
Ordered Locus Names:CLK_1539Imported
OrganismiClostridium botulinum (strain Loch Maree / Type A3)Imported
Taxonomic identifieri498214 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000000722: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi498214.CLK_1539.

Structurei

3D structure databases

ProteinModelPortaliB1KV90.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0610.
HOGENOMiHOG000003518.
KOiK01153.
OMAiPEKGRDK.
OrthoDBiEOG6JTCB4.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR006935. Helicase/UvrB_dom.
IPR014001. Helicase_ATP-bd.
IPR027417. P-loop_NTPase.
IPR007409. Restrct_endonuc_type1_HsdR_N.
IPR004473. Restrct_endonuc_typeI_HsdR.
IPR022625. TypeI_RM_Rsu_C.
[Graphical view]
PfamiPF12008. EcoR124_C. 1 hit.
PF04313. HSDR_N. 1 hit.
PF04851. ResIII. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 3 hits.
TIGRFAMsiTIGR00348. hsdR. 1 hit.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1KV90-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYQSEAELE KQLIKQLESK GYNKVKISTE EELIKNFRVQ LNKYNEEKLA
60 70 80 90 100
GTPLTDKEFE RVMRKVEGKS IFEGAKILRD KWPLKRDDGL EVYIEFFNSK
110 120 130 140 150
SLCKNIFQVT TQTTVVGKYT NRYDVTLLVN GLPLVQIELK RRGVDFKEAF
160 170 180 190 200
NQIQRYRKHS YQGLYRYIQI FIVSNGMDTK YFSNSDRDIL YTHTFFWTDE
210 220 230 240 250
KNQRISKLND FTDTFLERSF ISKIIARYMI INYTEKILMV MRPYQIYAVE
260 270 280 290 300
ALINRALETN GNGYIWHTTG SGKTLTSFKA SQILSKEPKI KKVFFLVDRK
310 320 330 340 350
DLDSQTINEF NKFEPKSVDV TDKTSTLIKQ IKDVNKPLIV TTIQKMANAI
360 370 380 390 400
KSPRYTKIME QYKDEKVAFI IDECHRSQFG SMHIAIEKHF KKAQYFGFTG
410 420 430 440 450
TPILKENKSQ DGRTTADLFD EMLHSYLIKD AIKDNNVLGF SVEYISTFKG
460 470 480 490 500
QFDENDDTKV KAIDKKEAFM DDERISQIAQ DIIKNHNKKT KDRQYTAIFA
510 520 530 540 550
VESIEMLVKY YDKFKKLDHN LKITGIFSYG VNEDAEGKDE HSRDSLEEII
560 570 580 590 600
KDYNEMFDTK YSTDTFQGYF ANVSKKVKSG QIDILIVVNM FLTGFDSKTL
610 620 630 640 650
NTLYIDKNLA YHSLIQAYSR TNRVYKSTKP YGNIVCYRNL KKKTDEAIKL
660 670 680 690 700
FSLTDNANEV LMKSYNHYLE AFKESVLNLY KIVPRPEDVD FIEGEKEKKE
710 720 730 740 750
FIVAFRELSK ILIKLQTFVE FEFDEDKLLI SEQTYQDFKS KYLAIYDSFK
760 770 780 790 800
NDEEGKASIL DDIDFGIELM HTDKINVDYI MNLIRNIDFS DKENKEKDIK
810 820 830 840 850
HIIKELDRAD SEHLRLKVDL LKSFLQEVVP NLTEEDSIDD AYSRFEQVQR
860 870 880 890 900
TEEIKAFSEQ AAVKEGKLKD YISEYEYSGM LDRKDMGDTI EGSFLKRKKV
910
VNKITTFIKN HVEKFS
Length:916
Mass (Da):107,404
Last modified:April 29, 2008 - v1
Checksum:i8504D735F452940C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000962 Genomic DNA. Translation: ACA55536.1.
RefSeqiWP_012343505.1. NC_010520.1.
YP_001787476.1. NC_010520.1.

Genome annotation databases

EnsemblBacteriaiACA55536; ACA55536; CLK_1539.
GeneIDi6154942.
KEGGicbl:CLK_1539.
PATRICi19389680. VBICloBot822_2453.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000962 Genomic DNA. Translation: ACA55536.1.
RefSeqiWP_012343505.1. NC_010520.1.
YP_001787476.1. NC_010520.1.

3D structure databases

ProteinModelPortaliB1KV90.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi498214.CLK_1539.

Protein family/group databases

REBASEi17443. CboA3ORF1538P.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACA55536; ACA55536; CLK_1539.
GeneIDi6154942.
KEGGicbl:CLK_1539.
PATRICi19389680. VBICloBot822_2453.

Phylogenomic databases

eggNOGiCOG0610.
HOGENOMiHOG000003518.
KOiK01153.
OMAiPEKGRDK.
OrthoDBiEOG6JTCB4.

Enzyme and pathway databases

BioCyciCBOT498214:GH05-2195-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR006935. Helicase/UvrB_dom.
IPR014001. Helicase_ATP-bd.
IPR027417. P-loop_NTPase.
IPR007409. Restrct_endonuc_type1_HsdR_N.
IPR004473. Restrct_endonuc_typeI_HsdR.
IPR022625. TypeI_RM_Rsu_C.
[Graphical view]
PfamiPF12008. EcoR124_C. 1 hit.
PF04313. HSDR_N. 1 hit.
PF04851. ResIII. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 3 hits.
TIGRFAMsiTIGR00348. hsdR. 1 hit.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids."
    Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C., Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S.
    PLoS ONE 2:E1271-E1271(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Loch Maree / Type A3Imported.

Entry informationi

Entry nameiB1KV90_CLOBM
AccessioniPrimary (citable) accession number: B1KV90
Entry historyi
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: March 4, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.