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B1KTZ5

- B1KTZ5_CLOBM

UniProt

B1KTZ5 - B1KTZ5_CLOBM

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Protein

Glutamate decarboxylase

Gene

CLK_1372

Organism
Clostridium botulinum (strain Loch Maree / Type A3)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.

Cofactori

Note: Pyridoxal phosphate.UniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciCBOT498214:GH05-2028-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:CLK_1372Imported
OrganismiClostridium botulinum (strain Loch Maree / Type A3)Imported
Taxonomic identifieri498214 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000000722: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi498214.CLK_1372.

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiKIHERTR.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

B1KTZ5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLYSSKNKQS NDTYATPIFG ITKDKYSIPK YKINENSIAP NIAYRMIKDE
60 70 80 90 100
LMNEGNARLN LATFCQTYME DKATKLMAET LQKNAIDKSE YPQTAEIENR
110 120 130 140 150
CVNIISDLWN VPKDMNFLGT STVGSSEACM LGGMSMKFRW RDQAKKLGID
160 170 180 190 200
INKKKPNLVI SSGYQVCWEK FCVYWDIEMR TVPMDEDNLS LNIDKILDYV
210 220 230 240 250
DEYTIGIIGI LGITYTGKFD DIKALDDAIE KYNSNHDMKV YIHVDAASGG
260 270 280 290 300
FFTPFINPEI LWDFRLKNVV SINASGHKYG LVYPGIGWIL WKDQEYLPKD
310 320 330 340 350
LIFEVSYLGG KMPTLAINFS RSGSQIIGQY YNFLRFGFEG YKKIHERTKE
360 370 380 390 400
VAMYISKELE ATGLFSIYND GSNLPIVCYK LKEQSNVKWN LYDLSDRLAM
410 420 430 440 450
KGWQIPAYPL PENLNHIIIQ RIVCRSDLGY NLAELLIKDF KTAINDLNNA
460
HILFHEEENQ GIYGFTH
Length:467
Mass (Da):53,664
Last modified:April 29, 2008 - v1
Checksum:i4BC052808BAA1A06
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000962 Genomic DNA. Translation: ACA53668.1.
RefSeqiWP_012341867.1. NC_010520.1.
YP_001787310.1. NC_010520.1.

Genome annotation databases

EnsemblBacteriaiACA53668; ACA53668; CLK_1372.
GeneIDi6152227.
KEGGicbl:CLK_1372.
PATRICi19389350. VBICloBot822_2288.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000962 Genomic DNA. Translation: ACA53668.1 .
RefSeqi WP_012341867.1. NC_010520.1.
YP_001787310.1. NC_010520.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 498214.CLK_1372.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACA53668 ; ACA53668 ; CLK_1372 .
GeneIDi 6152227.
KEGGi cbl:CLK_1372.
PATRICi 19389350. VBICloBot822_2288.

Phylogenomic databases

eggNOGi COG0076.
HOGENOMi HOG000070228.
KOi K01580.
OMAi KIHERTR.
OrthoDBi EOG6TFCPW.

Enzyme and pathway databases

BioCyci CBOT498214:GH05-2028-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
InterProi IPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfami PF00282. Pyridoxal_deC. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids."
    Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C., Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S.
    PLoS ONE 2:E1271-E1271(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Loch Maree / Type A3Imported.

Entry informationi

Entry nameiB1KTZ5_CLOBM
AccessioniPrimary (citable) accession number: B1KTZ5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: November 26, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3