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B1KSD1 (B1KSD1_CLOBM) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length386 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 RuleBase RU004247

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site381Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2671Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1361Substrate By similarity HAMAP-Rule MF_01201
Binding site3151Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue381N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
B1KSD1 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 4BD65F0C7A5E5313

FASTA38643,131
        10         20         30         40         50         60 
MFRNLRAVWA EIDLDNLQHN LKQIKKICGN KEIIGVIKAN AYGHGSMEIA PTLLENGVSR 

        70         80         90        100        110        120 
LAVAVLSEAM ELRMSGIKEP IMILGYTPCA LGDMLLDNDI EQSVYSYNDA LELSKIAVLK 

       130        140        150        160        170        180 
RKILKIHIVV DTGMGRIGFL PTKESVEDVY KISKLPNIQI EGVFSHFSSA DELDKDYTLY 

       190        200        210        220        230        240 
QMNNYNEFIN KLEEKNIQVH IKHIANSAAI IDLESTHLDA VRAGIIMYGY YPSNYVLRNN 

       250        260        270        280        290        300 
IKLKPVMSLK TSIVHIKKVS SGEYISYGRT FKTERESIIA TLPIGYADGY NRLLSNKGKV 

       310        320        330        340        350        360 
IVNGKLAPVI GRVCMDQCMI DVTSIENLKV GDVVTIMGEE NGVSYTAEDI ASQIGTISYE 

       370        380 
VICNVNKRVP RVYKKDGKII NVVNYV 

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References

[1]"Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids."
Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C., Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S.
PLoS ONE 2:E1271-E1271(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Loch Maree / Type A3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000962 Genomic DNA. Translation: ACA54762.1.
RefSeqYP_001788727.1. NC_010520.1.

3D structure databases

ProteinModelPortalB1KSD1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING498214.CLK_2830.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACA54762; ACA54762; CLK_2830.
GeneID6152080.
KEGGcbl:CLK_2830.
PATRIC19392270. VBICloBot822_3717.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMAFLGEDYH.
OrthoDBEOG6PP9NJ.
ProtClustDBPRK00053.

Enzyme and pathway databases

BioCycCBOT498214:GH05-3482-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1KSD1_CLOBM
AccessionPrimary (citable) accession number: B1KSD1
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: February 19, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)