ID   B1KQC7_SHEWM            Unreviewed;       807 AA.
AC   B1KQC7;
DT   29-APR-2008, integrated into UniProtKB/TrEMBL.
DT   29-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   RecName: Full=Adenylate cyclase {ECO:0000256|ARBA:ARBA00021420};
DE            EC=4.6.1.1 {ECO:0000256|ARBA:ARBA00012201};
DE   AltName: Full=ATP pyrophosphate-lyase {ECO:0000256|ARBA:ARBA00032597};
DE   AltName: Full=Adenylyl cyclase {ECO:0000256|ARBA:ARBA00032637};
GN   OrderedLocusNames=Swoo_0484 {ECO:0000313|EMBL:ACA84782.1};
OS   Shewanella woodyi (strain ATCC 51908 / MS32).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=392500 {ECO:0000313|EMBL:ACA84782.1, ECO:0000313|Proteomes:UP000002168};
RN   [1] {ECO:0000313|EMBL:ACA84782.1, ECO:0000313|Proteomes:UP000002168}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51908 / MS32 {ECO:0000313|Proteomes:UP000002168};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C.,
RA   Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Lykidis A., Zhao J.-S., Richardson P.;
RT   "Complete sequence of Shewanella woodyi ATCC 51908.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP = 3',5'-cyclic AMP + diphosphate; Xref=Rhea:RHEA:15389,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:58165; EC=4.6.1.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001593};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the adenylyl cyclase class-1 family.
CC       {ECO:0000256|ARBA:ARBA00007901, ECO:0000256|RuleBase:RU004184}.
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DR   EMBL; CP000961; ACA84782.1; -; Genomic_DNA.
DR   RefSeq; WP_012323131.1; NC_010506.1.
DR   AlphaFoldDB; B1KQC7; -.
DR   STRING; 392500.Swoo_0484; -.
DR   KEGG; swd:Swoo_0484; -.
DR   eggNOG; COG3072; Bacteria.
DR   HOGENOM; CLU_013280_0_0_6; -.
DR   Proteomes; UP000002168; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006171; P:cAMP biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR000274; Adenylate_cyclase_1.
DR   InterPro; IPR024686; Adenylate_cyclase_1_CS.
DR   InterPro; IPR024685; Adenylate_cyclase_1_N.
DR   InterPro; IPR043519; NT_sf.
DR   PANTHER; PTHR38760; ADENYLATE CYCLASE; 1.
DR   PANTHER; PTHR38760:SF1; ADENYLATE CYCLASE; 1.
DR   Pfam; PF12633; Adenyl_cycl_N; 1.
DR   Pfam; PF01295; Adenylate_cycl; 1.
DR   PIRSF; PIRSF001444; Adenylate_cycl; 2.
DR   SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR   PROSITE; PS01092; ADENYLATE_CYCLASE_1_1; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   cAMP biosynthesis {ECO:0000256|ARBA:ARBA00022998};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:ACA84782.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002168}.
FT   DOMAIN          8..204
FT                   /note="Adenylate cyclase class-I N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12633"
SQ   SEQUENCE   807 AA;  93025 MW;  26D138DD2F9D524E CRC64;
     MVNDQSHFVE TAQRLNRIRL ARALAILSPL KRDLLRLIPL LFHFHRVGYP GYNGPLTPSG
     IFNYQASESE YSACSTLGLV PPNLHLVNHP AIEGIYSMGS MASFGQNPKS DVDLWLVHDR
     LLSPNECRLL EEKSALISQW FEQYGLEVNI YLVHPEQFIK SSDSDEEFQT SIGLEHSGSA
     QHWLLLEEFY RSQICLAGKT VAWWPDAKRS EELLFLGDVS QIPASEYFGA SLWQLYKGLN
     KPHKALLKVL LLEAYASQYP NTCLVSGKVW QRTMEGDFSA ENDAYFLLYE SIESYLLAQD
     DLRRLDIVRR CFYLKCGLRL SEKNQAKDWR YHKLSMLVEN WKWSNSLLQT LDHCEDWHCG
     QLQWFNEQLN ELMLGSYQTL LQFASTQKLS KSLKLSELGL LTRKLHTYFS SDIQQIISLN
     RLWSDSVCEA DLTIIYSKNS QEYCLYRCKP APRNFIGQRA VYRSKSKAKL MAWACLNGVA
     NDATAWYEFS EGKRKSSSLS KASKRLVTFF EHADLRVSKM DFCQPWRYKK LVFLLNFNHD
     PTGLWQGQEI MVDYMNANIF SLGREQKNML ESIDIICLNS WGEWHCHHYE GEFGLLDALC
     FITAGIRRGA GDIAIEVISC STKLKSQFER TVGNLMQRAI RLSLQVSSSA TLVYPLKVSG
     IEYGLFFNSK GMVYQNLNDT KGLFQQLTKK KLLELPRPDL GNEPFSKVPE VIQDFAARGA
     IQYFLRQNEQ ELDVFILNES NELDHYQQSG IDIDELVSKV SHHHAFEEFK ASQQRFNLPQ
     FFRLIRVDGR LRALPFGISV DEVDFEF
//