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B1KPT4 (B1KPT4_SHEWM) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase HAMAP MF_00108
EC=2.7.7.60 HAMAP MF_00108
Alternative name(s):
4-diphosphocytidyl-2C-methyl-D-erythritol synthase HAMAP MF_00108
MEP cytidylyltransferase HAMAP MF_00108
Gene names
Name:ispD HAMAP MF_00108
Ordered Locus Names:Swoo_3348
OrganismShewanella woodyi (strain ATCC 51908 / MS32) [Complete proteome] [HAMAP] EMBL ACA87617.1
Taxonomic identifier392500 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length230 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) By similarity. HAMAP MF_00108

Catalytic activity

CTP + 2-C-methyl-D-erythritol 4-phosphate = diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol. HAMAP MF_00108

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 2/6. HAMAP MF_00108

Sequence similarities

Belongs to the IspD family. HAMAP MF_00108

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Site201Transition state stabilizer By similarity HAMAP MF_00108
Site271Transition state stabilizer By similarity HAMAP MF_00108
Site1561Positions MEP for the nucleophilic attack By similarity HAMAP MF_00108
Site2121Positions MEP for the nucleophilic attack By similarity HAMAP MF_00108

Sequences

Sequence LengthMass (Da)Tools
B1KPT4 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 5293E0257CF9108B

FASTA23024,713
        10         20         30         40         50         60 
MNDPQDKVVA LVPAAGIGSR MGSEIPKQYL EINGVPILNI TLTVLLTHPK IDVVIVALHP 

        70         80         90        100        110        120 
EDTLFHTLSQ SSNPKLRTVV GGGERADSVL ACLGEVEDNV WALVHDAARP CLSHEDIDKL 

       130        140        150        160        170        180 
LASRLEFPQG AILAAPVRDT MKRSNTGGTI VQTVCREQLW HALTPQLFLG SALRDNLASA 

       190        200        210        220        230 
LRQGVTVTDE ASAMEWAGNA PGLVSGNVKN IKITHPDDLK LAKLFLADEL

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References

[1]"Complete sequence of Shewanella woodyi ATCC 51908."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Lykidis A., Zhao J.-S., Richardson P.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 51908 / MS32.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000961 Genomic DNA. Translation: ACA87617.1.
RefSeqYP_001761712.1. NC_010506.1.

3D structure databases

ProteinModelPortalB1KPT4.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1KPT4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6117680.
GenomeReviewsGene locus Swoo_3348 in contig CP000961_GR.
KEGGswd:Swoo_3348.
PATRIC23609291. VBISheWoo126588_3447.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG672839.
OMAFPQGAIL.
ProtClustDBPRK00155.

Family and domain databases

HAMAPMF_00108. IspD.
[Tree]
InterProIPR001228. ISPD_synthase.
[Graphical view]
KOK00991.
PfamPF01128. IspD. 1 hit.
[Graphical view]
TIGRFAMsTIGR00453. IspD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB1KPT4_SHEWM
AccessionPrimary (citable) accession number: B1KPT4
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info