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B1KI57

- RNC_SHEWM

UniProt

B1KI57 - RNC_SHEWM

Protein

Ribonuclease 3

Gene

rnc

Organism
Shewanella woodyi (strain ATCC 51908 / MS32)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 45 (01 Oct 2014)
      Sequence version 1 (29 Apr 2008)
      Previous versions | rss
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    Functioni

    Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.UniRule annotation

    Catalytic activityi

    Endonucleolytic cleavage to 5'-phosphomonoester.UniRule annotation

    Cofactori

    Mg2+.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi42 – 421MagnesiumUniRule annotation
    Active sitei46 – 461UniRule annotation
    Metal bindingi115 – 1151MagnesiumUniRule annotation
    Active sitei118 – 1181UniRule annotation
    Metal bindingi118 – 1181MagnesiumUniRule annotation

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. ribonuclease III activity Source: UniProtKB-HAMAP
    3. rRNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. mRNA processing Source: UniProtKB-HAMAP
    2. rRNA catabolic process Source: InterPro
    3. rRNA processing Source: UniProtKB-HAMAP
    4. tRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    mRNA processing, rRNA processing, tRNA processing

    Keywords - Ligandi

    Magnesium, Metal-binding, RNA-binding, rRNA-binding

    Enzyme and pathway databases

    BioCyciSWOO392500:GI2C-1261-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease 3UniRule annotation (EC:3.1.26.3UniRule annotation)
    Alternative name(s):
    Ribonuclease IIIUniRule annotation
    Short name:
    RNase IIIUniRule annotation
    Gene namesi
    Name:rncUniRule annotation
    Ordered Locus Names:Swoo_1243
    OrganismiShewanella woodyi (strain ATCC 51908 / MS32)
    Taxonomic identifieri392500 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
    ProteomesiUP000002168: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 225225Ribonuclease 3PRO_1000094132Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi392500.Swoo_1243.

    Structurei

    3D structure databases

    ProteinModelPortaliB1KI57.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini7 – 129123RNase IIIUniRule annotationAdd
    BLAST
    Domaini155 – 22571DRBMUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 DRBM (double-stranded RNA-binding) domain.UniRule annotation
    Contains 1 RNase III domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0571.
    HOGENOMiHOG000246809.
    KOiK03685.
    OMAiHRFPKVN.
    OrthoDBiEOG6T1WVS.

    Family and domain databases

    Gene3Di1.10.1520.10. 1 hit.
    3.30.160.20. 1 hit.
    HAMAPiMF_00104. RNase_III.
    InterProiIPR014720. dsRNA-bd_dom.
    IPR011907. RNase_III.
    IPR000999. RNase_III_dom.
    [Graphical view]
    PANTHERiPTHR11207. PTHR11207. 1 hit.
    PfamiPF00035. dsrm. 1 hit.
    PF14622. Ribonucleas_3_3. 1 hit.
    [Graphical view]
    SMARTiSM00358. DSRM. 1 hit.
    SM00535. RIBOc. 1 hit.
    [Graphical view]
    SUPFAMiSSF69065. SSF69065. 1 hit.
    TIGRFAMsiTIGR02191. RNaseIII. 1 hit.
    PROSITEiPS50137. DS_RBD. 1 hit.
    PS00517. RNASE_3_1. 1 hit.
    PS50142. RNASE_3_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B1KI57-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEPIKNIPRL CRTLGYDFSE LALLDHALTH RSAASKHNER LEFLGDSILS    50
    IIISDALYHQ FPKATEGDLS RMRATLVCGK MLAEIGFEFK LGDYLKLGPG 100
    ELKSGGFRRE SIIADAVEAI IGAVYLDSDL EVTRSLVLGW YKTRLETIQP 150
    INQKDPKTLL QELLQGYKKP LPVYKVTDIR GEAHAQTFTI ECYVEELRKP 200
    VVGVASSRRK AEQLAAAQAL ELIKR 225
    Length:225
    Mass (Da):25,213
    Last modified:April 29, 2008 - v1
    Checksum:i81A90C7030170A77
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000961 Genomic DNA. Translation: ACA85535.1.
    RefSeqiWP_012323881.1. NC_010506.1.
    YP_001759630.1. NC_010506.1.

    Genome annotation databases

    EnsemblBacteriaiACA85535; ACA85535; Swoo_1243.
    GeneIDi6115478.
    KEGGiswd:Swoo_1243.
    PATRICi23604787. VBISheWoo126588_1289.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000961 Genomic DNA. Translation: ACA85535.1 .
    RefSeqi WP_012323881.1. NC_010506.1.
    YP_001759630.1. NC_010506.1.

    3D structure databases

    ProteinModelPortali B1KI57.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 392500.Swoo_1243.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACA85535 ; ACA85535 ; Swoo_1243 .
    GeneIDi 6115478.
    KEGGi swd:Swoo_1243.
    PATRICi 23604787. VBISheWoo126588_1289.

    Phylogenomic databases

    eggNOGi COG0571.
    HOGENOMi HOG000246809.
    KOi K03685.
    OMAi HRFPKVN.
    OrthoDBi EOG6T1WVS.

    Enzyme and pathway databases

    BioCyci SWOO392500:GI2C-1261-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1520.10. 1 hit.
    3.30.160.20. 1 hit.
    HAMAPi MF_00104. RNase_III.
    InterProi IPR014720. dsRNA-bd_dom.
    IPR011907. RNase_III.
    IPR000999. RNase_III_dom.
    [Graphical view ]
    PANTHERi PTHR11207. PTHR11207. 1 hit.
    Pfami PF00035. dsrm. 1 hit.
    PF14622. Ribonucleas_3_3. 1 hit.
    [Graphical view ]
    SMARTi SM00358. DSRM. 1 hit.
    SM00535. RIBOc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF69065. SSF69065. 1 hit.
    TIGRFAMsi TIGR02191. RNaseIII. 1 hit.
    PROSITEi PS50137. DS_RBD. 1 hit.
    PS00517. RNASE_3_1. 1 hit.
    PS50142. RNASE_3_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51908 / MS32.

    Entry informationi

    Entry nameiRNC_SHEWM
    AccessioniPrimary (citable) accession number: B1KI57
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: April 29, 2008
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3