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B1KB47 (XYLA_BURCC) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Xylose isomerase
EC=5.3.1.5
Gene names
Name:xylA
Ordered Locus Names:Bcenmc03_6329
OrganismBurkholderia cenocepacia (strain MC0-3) [Complete proteome] [HAMAP]
Taxonomic identifier406425 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex ›

Protein attributes

Sequence length440 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP-Rule MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP-Rule MF_00455

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00455

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00455.

Sequence similarities

Belongs to the xylose isomerase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-xylose metabolic process

Inferred from electronic annotation. Source: HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 440440Xylose isomerase HAMAP-Rule MF_00455
PRO_1000200282

Sites

Active site1001 By similarity
Active site1031 By similarity
Metal binding2311Magnesium 1 By similarity
Metal binding2671Magnesium 1 By similarity
Metal binding2671Magnesium 2 By similarity
Metal binding2701Magnesium 2 By similarity
Metal binding2951Magnesium 1 By similarity
Metal binding3061Magnesium 2 By similarity
Metal binding3081Magnesium 2 By similarity
Metal binding3381Magnesium 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
B1KB47 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 59C5F4B18709920F

FASTA44049,533
        10         20         30         40         50         60 
MSYFEHIPAI RYEGPQSDNP LAYHHYDPDK RVLGKTLAEH LRIAVCYWHT FVWPGHDIFG 

        70         80         90        100        110        120 
QGAFQRPWQQ PGDALERARQ KADAAFEFFT KLGTPFYTFH DTDVAPEGDS LRDYAANFAR 

       130        140        150        160        170        180 
MVDYLGERQH ASGVRLLWGT ANLFSHPRFA AGAATNPNPD VFAWAATQVC HALDATHRLG 

       190        200        210        220        230        240 
GENYVLWGGR EGYETLLNTD LKRERDQFAR FLSMVVEHKH RIGFKGALLI EPKPQEPTKH 

       250        260        270        280        290        300 
QYDYDVATVH GFLVQYGLQN EIRVNIEANH ATLAGHSFHH EIANAFALGV FGSVDANRGD 

       310        320        330        340        350        360 
PQNGWDTDQF PNSVEELTLA FYEILRHGGF TTGGMNFDAK VRRQSIDPED LFYGHVGAID 

       370        380        390        400        410        420 
VLALALERAA VLVENDRLDA LRRQRYAQWD DAFGRKILSG GYTLESLAAD ALARGVNPRH 

       430        440 
ASGAQERLEN IVNQAIYGLR

« Hide

References

[1]"Complete sequence of chromosome 3 of Burkholderia cenocepacia MC0-3."
Copeland A., Lucas S., Lapidus A., Barry K., Bruce D., Goodwin L., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Tiedje J., Richardson P.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MC0-3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000960 Genomic DNA. Translation: ACA95444.1.
RefSeqYP_001773939.1. NC_010512.1.

3D structure databases

ProteinModelPortalB1KB47.
SMRB1KB47. Positions 2-438.
ModBaseSearch...

Protein-protein interaction databases

STRING406425.Bcenmc03_6329.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACA95444; ACA95444; Bcenmc03_6329.
GeneID6125252.
KEGGbcm:Bcenmc03_6329.
PATRIC19094332. VBIBurCen61509_3642.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2115.
HOGENOMHOG000252293.
KOK01805.
OMAHTFQHEL.
ProtClustDBPRK05474.

Enzyme and pathway databases

BioCycBCEN406425:GHD9-6411-MONOMER.

Family and domain databases

Gene3D3.20.20.150. 1 hit.
HAMAPMF_00455. Xylose_isom_A.
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR02630. xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYLA_BURCC
AccessionPrimary (citable) accession number: B1KB47
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: May 29, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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