B1K8V5 (B1K8V5_BURCC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183

Gene names

Ordered Locus Names:

Bcenmc03_3297

Organism

Burkholderia cenocepacia (strain MC0-3) [Complete proteome] [HAMAP]

Taxonomic identifier

406425 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	371 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183
Pathway	Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183
Sequence similarities	Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
Ligand	NAD PIRNR PIRNR000183
Molecular function	Oxidoreductase PIRNR PIRNR000183
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	alanine dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1K8V5 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 8F33CBF3389EFB32	FASTA	371	38,353
	10 20 30 40 50 60 MLIGVPKEIK NHEYRVGLTP AGARELTRHG HRVLVQRGAG TAIGLLDDDY TAAGASLGDG 70 80 90 100 110 120 AEEIFARADM IIKVKEPQPT ECAMLRRGQI LYTYLHLAPD PDQAAALVKS GAVCIAYETV 130 140 150 160 170 180 TGPGGGLPLL APMSEVAGRM SIQVAATHLE SPRGGRGLLM AGVPGVPAAH VVVLGAGVVG 190 200 210 220 230 240 TGALQMAVGL GARVTVLDNN VNRLRQLDLV FANRIATVCS NAQTVDEAVR DADVVIGAVL 250 260 270 280 290 300 VPGASAPRLV TRDMIATMRK GAVVVDVAID QGGCFETSHA TTHAAPTFVV DGVVHYCVAN 310 320 330 340 350 360 MPGAVARTST FALNNATLGH ALALADKGWK QAMLDDPHLR AGLNVCDGHI TYEAVALALG 370 LPYVPATGVL A

References

[1]

"Complete sequence of chromosome 2 of Burkholderia cenocepacia MC0-3." Copeland A., Lucas S., Lapidus A., Barry K., Bruce D., Goodwin L., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Mikhailova N., Tiedje J., Richardson P. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000959 Genomic DNA. Translation: ACA92452.1.
RefSeq	YP_001776942.1. NC_010515.1.
3D structure databases
ProteinModelPortal	B1K8V5.
SMR	B1K8V5. Positions 1-371.
ModBase	Search...
Protein-protein interaction databases
STRING	B1K8V5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6126032.
GenomeReviews	Gene locus Bcenmc03_3297 in contig CP000959_GR.
KEGG	bcm:Bcenmc03_3297.
PATRIC	19096167. VBIBurCen61509_4554.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289735.
OMA	AIGYETV.
ProtClustDB	CLSK931331.
Family and domain databases
InterPro	IPR008143. Ala_DH/PNT_CS2. IPR008141. Ala_DH/Pyr_transHydgase. IPR007886. AlaDH/PNT_N. IPR007698. AlaDH/PNT_NAD(H)-bd. [Graphical view]
KO	K00259.
PANTHER	PTHR10160:SF3. PTHR10160:SF3. 1 hit.
Pfam	PF01262. AlaDh_PNT_C. 1 hit. PF05222. AlaDh_PNT_N. 1 hit. [Graphical view]
PIRSF	PIRSF000183. Alanine_dh. 1 hit.
SMART	SM01002. AlaDh_PNT_C. 1 hit. SM01003. AlaDh_PNT_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00518. AlaDH. 1 hit.
PROSITE	PS00837. ALADH_PNT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B1K8V5_BURCC

Accession

Primary (citable) accession number: B1K8V5

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)