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B1K6Y5 (B1K6Y5_BURCC) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyrroloquinoline-quinone synthase HAMAP MF_00654

EC=1.3.3.11 HAMAP MF_00654
Alternative name(s):
Coenzyme PQQ synthesis protein C HAMAP MF_00654
Pyrroloquinoline quinone biosynthesis protein C HAMAP MF_00654
Gene names
Name:pqqC HAMAP MF_00654
Ordered Locus Names:Bcenmc03_5160
OrganismBurkholderia cenocepacia (strain MC0-3) [Complete proteome] [HAMAP]
Taxonomic identifier406425 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex

Protein attributes

Sequence length239 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity. HAMAP MF_00654

Catalytic activity

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O. HAMAP MF_00654

Pathway

Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. HAMAP MF_00654

Sequence similarities

Belongs to the pqqC family. HAMAP MF_00654

Ontologies

Sequences

Sequence LengthMass (Da)Tools
B1K6Y5 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 0176D5E7588FA9D5

FASTA23927,225
        10         20         30         40         50         60 
MNAPIPATAL HATPWTATEF EARLRALESR YHIHHPFNRR LNSGACSPTQ IRGWVANRFY 

        70         80         90        100        110        120 
YQICIPLKDA AILSNCPDRD TRRRWIQRLI DHDGQGDNAG GIEAWVRLGE ACGLARDELW 

       130        140        150        160        170        180 
SLEHVLPGVR FAVDAYVNFA RRAPWQEAVC SSLTEMFAPQ IHLDRLAGWP SHYPWIEPAG 

       190        200        210        220        230 
LHYFRSRVPL AQRDVEHGLA VTLAHFTTPD AQQRALGILQ FKLDILWSML DAVEKAYPL 

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References

[1]"Complete sequence of chromosome 2 of Burkholderia cenocepacia MC0-3."
Copeland A., Lucas S., Lapidus A., Barry K., Bruce D., Goodwin L., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Tiedje J., Richardson P.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000959 Genomic DNA. Translation: ACA94289.1.
RefSeqYP_001778779.1. NC_010515.1.

3D structure databases

ProteinModelPortalB1K6Y5.
SMRB1K6Y5. Positions 20-239.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1K6Y5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6127971.
GenomeReviewsGene locus Bcenmc03_5160 in contig CP000959_GR.
KEGGbcm:Bcenmc03_5160.
PATRIC19099980. VBIBurCen61509_6451.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG288944.
OMADSWPQHY.
ProtClustDBPRK05157.

Family and domain databases

HAMAPMF_00654. PQQ_syn_PqqC.
[Tree]
InterProIPR016084. Haem_Oase-like_multi-hlx.
IPR011845. PQQ_synth_PqqC.
IPR004305. TENA/THI4/PQQ_synthPqqC_dom.
[Graphical view]
Gene3DG3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
KOK06137.
PfamPF03070. TENA_THI-4. 1 hit.
[Graphical view]
SUPFAMSSF48613. Heme_oxygenase. 1 hit.
TIGRFAMsTIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB1K6Y5_BURCC
AccessionPrimary (citable) accession number: B1K6Y5
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)