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B1K297 (B1K297_BURCC) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable L-aspartate dehydrogenase HAMAP MF_01265
EC=1.4.1.21 HAMAP MF_01265
Gene names
Name:nadX HAMAP MF_01265
Ordered Locus Names:Bcenmc03_5598
OrganismBurkholderia cenocepacia (strain MC0-3) [Complete proteome] [HAMAP]
Taxonomic identifier406425 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length275 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate By similarity. HAMAP MF_01265

Catalytic activity

L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H. HAMAP MF_01265

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. HAMAP MF_01265

Miscellaneous

The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia By similarity. HAMAP MF_01265

Sequence similarities

Belongs to the L-aspartate dehydrogenase family. HAMAP MF_01265

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2281 By similarity HAMAP MF_01265
Binding site1321NAD; via amide nitrogen By similarity HAMAP MF_01265
Binding site1981NAD By similarity HAMAP MF_01265

Sequences

Sequence LengthMass (Da)Tools
B1K297 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: AB0136BC54F88DB9

FASTA27528,589
        10         20         30         40         50         60 
MHNGQKRARA PVDVAMIGFG AIGAAVYRAV EHDASLRVAH VIVPEHQRAA VQRELGGAVE 

        70         80         90        100        110        120 
VVSSVDALAR RPEFALECAG HGALVDHVVP LLKAGTDCAV ASIGALSDLA LLDVLSRAAD 

       130        140        150        160        170        180 
EGGTTVTLLS GAIGGIDALA SAKEGGLDEV RYVGRKPPLG WLGTPAEELC DLRAMTEEKV 

       190        200        210        220        230        240 
IFEGSARDAA RLYPKNANVA ATVALAGLGL DATHVRLIAD PAVERNVHRI TARGAFGEMS 

       250        260        270 
LEMSGKPLPD NPKTSALTAY SAIRALRNRA ACCVI

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References

[1]"Complete sequence of chromosome 2 of Burkholderia cenocepacia MC0-3."
Copeland A., Lucas S., Lapidus A., Barry K., Bruce D., Goodwin L., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Tiedje J., Richardson P.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000959 Genomic DNA. Translation: ACA94723.1.
RefSeqYP_001779213.1. NC_010515.1.

3D structure databases

ProteinModelPortalB1K297.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1K297.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6128406.
GenomeReviewsGene locus Bcenmc03_5598 in contig CP000959_GR.
KEGGbcm:Bcenmc03_5598.
PATRIC19100876. VBIBurCen61509_6896.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG649642.
OMAECAGHSA.
ProtClustDBPRK13303.

Family and domain databases

HAMAPMF_01265. NadX.
[Tree]
InterProIPR005106. Asp/hSer_DH_NAD-bd.
IPR002811. Asp_DH.
IPR011182. Asp_DH_NAD_syn.
IPR020626. Asp_DH_NAD_syn_prok.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK06989.
PfamPF01958. DUF108. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFPIRSF005227. Asp_dh_NAD_syn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB1K297_BURCC
AccessionPrimary (citable) accession number: B1K297
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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