Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

B1K259 (ADC_BURCC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable acetoacetate decarboxylase

Short name=AAD
Short name=ADC
EC=4.1.1.4
Gene names
Name:adc
Ordered Locus Names:Bcenmc03_4525
OrganismBurkholderia cenocepacia (strain MC0-3) [Complete proteome] [HAMAP]
Taxonomic identifier406425 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex

Protein attributes

Sequence length246 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of acetoacetate to acetone and carbon dioxide By similarity. HAMAP-Rule MF_00597

Catalytic activity

Acetoacetate = acetone + CO2. HAMAP-Rule MF_00597

Sequence similarities

Belongs to the ADC family.

Ontologies

Keywords
   LigandSchiff base
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionacetoacetate decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 246246Probable acetoacetate decarboxylase HAMAP-Rule MF_00597
PRO_1000129875

Sites

Active site1161Schiff-base intermediate with acetoacetate By similarity

Sequences

Sequence LengthMass (Da)Tools
B1K259 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: B98A02343AAABE49

FASTA24627,454
        10         20         30         40         50         60 
MKPSDVRSKA FAMPLTSPAF PMGPYRFVDR EFLIITYRTD PDRLREIVPE PLQVTEPLVH 

        70         80         90        100        110        120 
YEFIRMADST GFGDYTESGQ VIPVEYEGQP GGYTLAMYLD DHPPIAGGRE LWGFPKKLAS 

       130        140        150        160        170        180 
PTLHVNTDHI LGTLDYGKVR VATGTMGYKH KELDIDEQTK RLAGPNFLLK IIPHVDGTAR 

       190        200        210        220        230        240 
VCELVRYYMQ DIKMKGAWTG PASLELAPHA LAPVADLPVL EIVEARHLVA DLTLGLGEVV 


YDYLAQ 

« Hide

References

[1]"Complete sequence of chromosome 2 of Burkholderia cenocepacia MC0-3."
Copeland A., Lucas S., Lapidus A., Barry K., Bruce D., Goodwin L., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Tiedje J., Richardson P.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MC0-3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000959 Genomic DNA. Translation: ACA93665.1.
RefSeqYP_001778155.1. NC_010515.1.

3D structure databases

ProteinModelPortalB1K259.
SMRB1K259. Positions 4-245.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING406425.Bcenmc03_4525.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACA93665; ACA93665; Bcenmc03_4525.
GeneID6127347.
KEGGbcm:Bcenmc03_4525.
PATRIC19098722. VBIBurCen61509_5827.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG4689.
HOGENOMHOG000063822.
KOK01574.
OMAEYLHAMY.
OrthoDBEOG60CWK7.
ProtClustDBPRK02265.

Enzyme and pathway databases

BioCycBCEN406425:GHD9-4603-MONOMER.

Family and domain databases

Gene3D2.40.400.10. 1 hit.
HAMAPMF_00597. ADC.
InterProIPR010451. Acetoacetate_decarboxylase.
IPR023653. Acetoacetate_decarboxylase_bac.
IPR023375. Acetoacetate_decarboxylase_dom.
[Graphical view]
PfamPF06314. ADC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameADC_BURCC
AccessionPrimary (citable) accession number: B1K259
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: April 16, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families