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B1K219 (B1K219_BURCC) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase 2 HAMAP MF_01201
EC=5.1.1.1 HAMAP MF_01201
Gene names
Name:alr2 HAMAP MF_01201
Ordered Locus Names:Bcenmc03_3445
OrganismBurkholderia cenocepacia (strain MC0-3) [Complete proteome] [HAMAP]
Taxonomic identifier406425 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length373 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201 SAAS SAAS009006

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site351Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201
Active site2521Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201

Amino acid modifications

Modified residue351N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201

Sequences

Sequence LengthMass (Da)Tools
B1K219 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: DC031A44AD0AF6AE

FASTA37340,306
        10         20         30         40         50         60 
MPRPIVAHIR PDAVRHNLDF IRRTAAQSRV WAVVKANAYG HGIERIYPGL AAADGIGLLD 

        70         80         90        100        110        120 
LDEAVRVREL GWDKPVLLLE GVFEPADVEL ADRHRLTVAV HCDEQLDLLI AAKPRQPIDI 

       130        140        150        160        170        180 
QLKMNSGMNR LGYRPAAFRA AWERAANAPS IGKITLMMHF ANADEGEVDW QLDQFDATTA 

       190        200        210        220        230        240 
GIPGERSVSN SAAVLWHPRA HRDWVRPGTI LYGASPTGAA RHIADTPLMA AMTLSSKIIG 

       250        260        270        280        290        300 
VQTLAPDETV GYGRRFTADR PMRIGVVACG YADGYPRHAP TGTPIAVDGV MTRVVGRVSM 

       310        320        330        340        350        360 
DMLTVDLTPC PNAGIGSRVE LWGDQVKVDD VAQASGTIGY ELMCALARRV PVVIVPPGAA 

       370 
SVQPALRTGS YGR

« Hide

References

[1]"Complete sequence of chromosome 2 of Burkholderia cenocepacia MC0-3."
Copeland A., Lucas S., Lapidus A., Barry K., Bruce D., Goodwin L., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Tiedje J., Richardson P.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000959 Genomic DNA. Translation: ACA92598.1.
RefSeqYP_001777088.1. NC_010515.1.

3D structure databases

ProteinModelPortalB1K219.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1K219.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6126280.
GenomeReviewsGene locus Bcenmc03_3445 in contig CP000959_GR.
KEGGbcm:Bcenmc03_3445.
PATRIC19096487. VBIBurCen61509_4714.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG712172.
OMACISAEEM.
ProtClustDBPRK13340.

Family and domain databases

HAMAPMF_01201. Ala_racemase.
[Tree]
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
KOK01775.
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. Alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1K219_BURCC
AccessionPrimary (citable) accession number: B1K219
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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