Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cobalt-precorrin-5B C(1)-methyltransferase

Gene

cbiD

Organism
Burkholderia cenocepacia (strain MC0-3)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.UniRule annotation

Catalytic activityi

Cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A + S-adenosyl-L-homocysteine.UniRule annotation

Pathwayi: adenosylcobalamin biosynthesis

This protein is involved in step 6 of the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route).UniRule annotation
Proteins known to be involved in the 10 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
  6. Cobalt-precorrin-5B C(1)-methyltransferase (cbiD)
  7. no protein annotated in this organism
  8. no protein annotated in this organism
  9. no protein annotated in this organism
  10. no protein annotated in this organism
This subpathway is part of the pathway adenosylcobalamin biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route), the pathway adenosylcobalamin biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processCobalamin biosynthesis
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciBCEN406425:G1GBC-1759-MONOMER
UniPathwayiUPA00148; UER00227

Names & Taxonomyi

Protein namesi
Recommended name:
Cobalt-precorrin-5B C(1)-methyltransferaseUniRule annotation (EC:2.1.1.195UniRule annotation)
Alternative name(s):
Cobalt-precorrin-6A synthaseUniRule annotation
Gene namesi
Name:cbiDUniRule annotation
Ordered Locus Names:Bcenmc03_1649
OrganismiBurkholderia cenocepacia (strain MC0-3)
Taxonomic identifieri406425 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
Proteomesi
  • UP000002169 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001337281 – 362Cobalt-precorrin-5B C(1)-methyltransferaseAdd BLAST362

Structurei

3D structure databases

ProteinModelPortaliB1K168
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CbiD family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000009126
KOiK02188
OMAiGGIFHTH
OrthoDBiPOG091H02QJ

Family and domain databases

Gene3Di3.30.2110.10, 1 hit
HAMAPiMF_00787 CbiD, 1 hit
InterProiView protein in InterPro
IPR002748 CbiD
IPR036074 CbiD_sf
PANTHERiPTHR35863 PTHR35863, 1 hit
PfamiView protein in Pfam
PF01888 CbiD, 1 hit
PIRSFiPIRSF026782 CbiD, 1 hit
SUPFAMiSSF111342 SSF111342, 1 hit
TIGRFAMsiTIGR00312 cbiD, 1 hit

Sequencei

Sequence statusi: Complete.

B1K168-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRDETPEQPA PLRFGYTTGS CATATSLAAA RLLLAGQADD AVEIVLPKGQ
60 70 80 90 100
RVMMRLEFCR ATADGAEAGT IKDAGDDPDV THGALIFARV ALAAAPGVRF
110 120 130 140 150
HAGPGVGTVT RAGLMLPVGE PAINPVPRQM MTTHLEALAA EHGYAGGFDV
160 170 180 190 200
TIGVEGGEML ALKTMNPRLG IVGGLSILGT TGIVRPFSCS AYIASIHQGI
210 220 230 240 250
DVARANGIAH IAACTGNASE DAMRAHYQLP DMALIEMGDF AGAVLKHLRR
260 270 280 290 300
APVARLSMCG GFGKLSKLAA GHLDLHSRHS SIDLPLLAQW AAEAGANDAL
310 320 330 340 350
QAAMRAANTS QEALKLAQAD GVPLGDLVCA HALRVARDIV PPSVVIEMFA
360
IDRQGRFVGV AR
Length:362
Mass (Da):37,584
Last modified:April 29, 2008 - v1
Checksum:i3B1F613558B53811
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000958 Genomic DNA Translation: ACA90822.1
RefSeqiWP_012328487.1, NC_010508.1

Genome annotation databases

EnsemblBacteriaiACA90822; ACA90822; Bcenmc03_1649
KEGGibcm:Bcenmc03_1649

Similar proteinsi

Entry informationi

Entry nameiCBID_BURCC
AccessioniPrimary (citable) accession number: B1K168
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: March 28, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health