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B1K0S6

- LFTR_BURCC

UniProt

B1K0S6 - LFTR_BURCC

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Protein
Leucyl/phenylalanyl-tRNA--protein transferase
Gene
aat, Bcenmc03_1532
Organism
Burkholderia cenocepacia (strain MC0-3)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine By similarity.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

  1. leucyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

BioCyciBCEN406425:GHD9-1577-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferase (EC:2.3.2.6)
Alternative name(s):
L/F-transferase
Leucyltransferase
Phenyalanyltransferase
Gene namesi
Name:aat
Ordered Locus Names:Bcenmc03_1532
OrganismiBurkholderia cenocepacia (strain MC0-3)
Taxonomic identifieri406425 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000002169: Chromosome 1

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 254254Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation
PRO_1000131907Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi406425.Bcenmc03_1532.

Structurei

3D structure databases

ProteinModelPortaliB1K0S6.

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.

Phylogenomic databases

eggNOGiCOG2360.
HOGENOMiHOG000102325.
KOiK00684.
OMAiWSPDPRG.
OrthoDBiEOG6WX4R3.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.

Sequencei

Sequence statusi: Complete.

B1K0S6-1 [UniParc]FASTAAdd to Basket

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MVPWLGPDDP FPSIERALGP ATGAPGLLAA SADLLPSRLI DAYLRGIFPW    50
YSDGQPVLWW SPDPRMILVP AEFKVSPSLR KTLKRVLRAP EWEVRVDHDF 100
AGVMRACAQA PRRGQRGTWI TAEIIDAYTS LYRSGNAHSI ETWHDGRRVG 150
GLYGVSFGRM FFGESMYADV TDASKIALAA LIAHLREQGL EMIDCQQNTS 200
HLASLGGREI ARKAFVAHVR SAVAEPPIPW QFDKRVLAAL TSPAETAAPT 250
GTER 254
Length:254
Mass (Da):27,931
Last modified:April 29, 2008 - v1
Checksum:i129FF33DC923A745
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000958 Genomic DNA. Translation: ACA90707.1.
RefSeqiYP_001764829.1. NC_010508.1.

Genome annotation databases

EnsemblBacteriaiACA90707; ACA90707; Bcenmc03_1532.
GeneIDi6123210.
KEGGibcm:Bcenmc03_1532.
PATRICi19090144. VBIBurCen61509_1585.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000958 Genomic DNA. Translation: ACA90707.1 .
RefSeqi YP_001764829.1. NC_010508.1.

3D structure databases

ProteinModelPortali B1K0S6.
ModBasei Search...

Protein-protein interaction databases

STRINGi 406425.Bcenmc03_1532.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACA90707 ; ACA90707 ; Bcenmc03_1532 .
GeneIDi 6123210.
KEGGi bcm:Bcenmc03_1532.
PATRICi 19090144. VBIBurCen61509_1585.

Phylogenomic databases

eggNOGi COG2360.
HOGENOMi HOG000102325.
KOi K00684.
OMAi WSPDPRG.
OrthoDBi EOG6WX4R3.

Enzyme and pathway databases

BioCyci BCEN406425:GHD9-1577-MONOMER.

Family and domain databases

HAMAPi MF_00688. Leu_Phe_trans.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view ]
Pfami PF03588. Leu_Phe_trans. 1 hit.
[Graphical view ]
SUPFAMi SSF55729. SSF55729. 1 hit.
TIGRFAMsi TIGR00667. aat. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 1 of Burkholderia cenocepacia MC0-3."
    Copeland A., Lucas S., Lapidus A., Barry K., Bruce D., Goodwin L., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L.
    , Kyrpides N., Mikhailova N., Tiedje J., Richardson P.
    Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MC0-3.

Entry informationi

Entry nameiLFTR_BURCC
AccessioniPrimary (citable) accession number: B1K0S6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: May 14, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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