B1JYS3 (B1JYS3_BURCC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	Bcenmc03_2837

Organism

Burkholderia cenocepacia (strain MC0-3) [Complete proteome] [HAMAP] EMBL ACA91996.1

Taxonomic identifier

406425 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	1071 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS023073
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1JYS3 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 2CE8192C79D71891	FASTA	1,071	118,745
	10 20 30 40 50 60 MVAEFSLLPD YAELFCRSNF SFLHGASHAE ELVERADELG YRGIAITDEC SLAGAPRMHV 70 80 90 100 110 120 AAKEKGLPLV IGSYFDVTPD EVAPGHDPGP GAFGLVLLAQ NREGYGNLSE LISWRRMEAP 130 140 150 160 170 180 KGTYKLTSRI LSAPPAKFAH LRGMPDCFAI LVPTYPVRAD VLDAQVAWFR ATFGERARLG 190 200 210 220 230 240 LVQLQRALDG VQRDEIRAAG KRRGVRLVAL GDVTMHVRSC KALQDVMTAI RVGMPVAECG 250 260 270 280 290 300 YALAPNAEQH LRSRGRIAKL FSAEEIGETC AMLDACDFDL DDLKYEYPLE LVPRGHTPTS 310 320 330 340 350 360 YLKQETWAGV ARRYWNGVPE KVAKQIRYEL ALIAKLEYEP FFLTVYDIVK YARSQNILCQ 370 380 390 400 410 420 GRGSAANSVV CYCLGITEVN PDQSTMLFER FISEKRGEPP DIDVDFEHQR REEVIQHIYK 430 440 450 460 470 480 KYGKDRAALA AAVSTYRPRG VLRETGKALS VDPMLVDRVA KGHRWFDGSR DLLQQFASTG 490 500 510 520 530 540 LDPATPIIQT WAELAGRLLN FPRHLSQHSG GFVISRGKLT RLVPVENAAM DGRRVIQWDK 550 560 570 580 590 600 DDLEALGLMK VDVLALGMLS ALHRAFDLRT AWRGPAKDGK PFTLKHIPQD DKATYDMICR 610 620 630 640 650 660 ADTVGVFQIE SRAQMSMLPR LRPRNYYDLV VQVSIVRPGP IQGGAVHPYL KRRRIVAGEE 670 680 690 700 710 720 KGEVTYPSDA LKEVLVRTLG VPIFQEQVMQ IAIVAAGFTP GEADDLRRAM AAWKRKGNLE 730 740 750 760 770 780 KYQDKIISGM LERNYTREFA EQIFEQIKGF GEYGFPESHA ASFAKLAYAS SWLKCHEPAI 790 800 810 820 830 840 FLAALLNSQP MGFYPPSQLV QDAKRHRVKV LPIDVTQSGW EASLEALPDQ PPPHGQPAVR 850 860 870 880 890 900 LGLSLVRGLS EAAARRIEAA RTAGPFDSVD SLARRAQLER RDLEALAAAN ALATLAGHRR 910 920 930 940 950 960 DALWQAVAAA PERDLLAAAP IDEVEQPALG APSEADDILA DYHTTGLTLN RHPVALLRPA 970 980 990 1000 1010 1020 LRAQRLSSAA ELRDRPDGRL ARACGLVIAR QMPGTAKGVM FMTLEDETGC VNVIVRPELL 1030 1040 1050 1060 1070 ARQRRETLDS RLLAASGVWQ VVSDVRHLVA QHFEDLTPLL GGLRTSSREF H

References

[1]

"Complete sequence of chromosome 1 of Burkholderia cenocepacia MC0-3." Copeland A., Lucas S., Lapidus A., Barry K., Bruce D., Goodwin L., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Mikhailova N., Tiedje J., Richardson P. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000958 Genomic DNA. Translation: ACA91996.1.
RefSeq	YP_001766118.1. NC_010508.1.
3D structure databases
ProteinModelPortal	B1JYS3.
ModBase	Search...
Protein-protein interaction databases
STRING	B1JYS3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6124499.
GenomeReviews	Gene locus Bcenmc03_2837 in contig CP000958_GR.
KEGG	bcm:Bcenmc03_2837.
PATRIC	19092928. VBIBurCen61509_2945.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734490.
OMA	IDEVEQP.
ProtClustDB	PRK05672.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1JYS3_BURCC

Accession

Primary (citable) accession number: B1JYS3

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)