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B1JXI7 (KYNB_BURCC) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Kynurenine formamidase

Short name=KFA
Short name=KFase
EC=3.5.1.9
Alternative name(s):
Arylformamidase
N-formylkynurenine formamidase
Short name=FKF
Gene names
Name:kynB
Ordered Locus Names:Bcenmc03_2601
OrganismBurkholderia cenocepacia (strain MC0-3) [Complete proteome] [HAMAP]
Taxonomic identifier406425 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex

Protein attributes

Sequence length213 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation By similarity. HAMAP-Rule MF_01969

Catalytic activity

N-formyl-L-kynurenine + H2O = formate + L-kynurenine. HAMAP-Rule MF_01969

Pathway

Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 2/2. HAMAP-Rule MF_01969

Sequence similarities

Belongs to the KynB family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 213213Kynurenine formamidase HAMAP-Rule MF_01969
PRO_0000362101

Sequences

Sequence LengthMass (Da)Tools
B1JXI7 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: EDFC1F20167A178B

FASTA21322,662
        10         20         30         40         50         60 
MDTLWDISPP VSPATPVWPG DTPVAVERVW RMEAGSPVNV ARLTLSPHTG AHCDAPLHYD 

        70         80         90        100        110        120 
ADGAPIGAVP LDTYLGPCRV IHCIGASPVV RPADVEVALD GVPPRVLLRT YARAAVEQWD 

       130        140        150        160        170        180 
SAFCAVAPDT VDLLAAHGVK LIGIDTPSLD PQESKTMDAH HRVRAHRMAI LEGIVLDDVP 

       190        200        210 
PGDYELIALP LKFATLDASP VRAVLRALPA HAS 

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References

[1]"Complete sequence of chromosome 1 of Burkholderia cenocepacia MC0-3."
Copeland A., Lucas S., Lapidus A., Barry K., Bruce D., Goodwin L., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Tiedje J., Richardson P.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MC0-3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000958 Genomic DNA. Translation: ACA91762.1.
RefSeqYP_001765884.1. NC_010508.1.

3D structure databases

ProteinModelPortalB1JXI7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING406425.Bcenmc03_2601.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACA91762; ACA91762; Bcenmc03_2601.
GeneID6124265.
KEGGbcm:Bcenmc03_2601.
PATRIC19092434. VBIBurCen61509_2700.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1878.
HOGENOMHOG000219455.
KOK07130.
OMAHTSKWPL.
OrthoDBEOG67T5JJ.

Enzyme and pathway databases

BioCycBCEN406425:GHD9-2673-MONOMER.
UniPathwayUPA00333; UER00454.

Family and domain databases

HAMAPMF_01969. KynB.
InterProIPR007325. Cyclase.
IPR017484. Kynurenine_formamidase_bac.
[Graphical view]
PfamPF04199. Cyclase. 1 hit.
[Graphical view]
TIGRFAMsTIGR03035. trp_arylform. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKYNB_BURCC
AccessionPrimary (citable) accession number: B1JXI7
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: April 29, 2008
Last modified: May 14, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways