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B1JXI7

- KYNB_BURCC

UniProt

B1JXI7 - KYNB_BURCC

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Protein

Kynurenine formamidase

Gene

kynB

Organism
Burkholderia cenocepacia (strain MC0-3)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.UniRule annotation

Catalytic activityi

N-formyl-L-kynurenine + H2O = formate + L-kynurenine.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. arylformamidase activity Source: UniProtKB
  2. formamidase activity Source: InterPro

GO - Biological processi

  1. anthranilate metabolic process Source: UniProtKB
  2. tryptophan catabolic process to kynurenine Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Tryptophan catabolism

Enzyme and pathway databases

BioCyciBCEN406425:GHD9-2673-MONOMER.
UniPathwayiUPA00333; UER00454.

Names & Taxonomyi

Protein namesi
Recommended name:
Kynurenine formamidaseUniRule annotation (EC:3.5.1.9UniRule annotation)
Short name:
KFAUniRule annotation
Short name:
KFaseUniRule annotation
Alternative name(s):
ArylformamidaseUniRule annotation
N-formylkynurenine formamidaseUniRule annotation
Short name:
FKFUniRule annotation
Gene namesi
Name:kynBUniRule annotation
Ordered Locus Names:Bcenmc03_2601
OrganismiBurkholderia cenocepacia (strain MC0-3)
Taxonomic identifieri406425 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000002169: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 213213Kynurenine formamidasePRO_0000362101Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi406425.Bcenmc03_2601.

Structurei

3D structure databases

ProteinModelPortaliB1JXI7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the KynB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1878.
HOGENOMiHOG000219455.
KOiK07130.
OMAiHTSKWPL.
OrthoDBiEOG67T5JJ.

Family and domain databases

HAMAPiMF_01969. KynB.
InterProiIPR007325. KFase.
IPR017484. Kynurenine_formamidase_bac.
[Graphical view]
PfamiPF04199. Cyclase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03035. trp_arylform. 1 hit.

Sequencei

Sequence statusi: Complete.

B1JXI7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDTLWDISPP VSPATPVWPG DTPVAVERVW RMEAGSPVNV ARLTLSPHTG
60 70 80 90 100
AHCDAPLHYD ADGAPIGAVP LDTYLGPCRV IHCIGASPVV RPADVEVALD
110 120 130 140 150
GVPPRVLLRT YARAAVEQWD SAFCAVAPDT VDLLAAHGVK LIGIDTPSLD
160 170 180 190 200
PQESKTMDAH HRVRAHRMAI LEGIVLDDVP PGDYELIALP LKFATLDASP
210
VRAVLRALPA HAS
Length:213
Mass (Da):22,662
Last modified:April 29, 2008 - v1
Checksum:iEDFC1F20167A178B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000958 Genomic DNA. Translation: ACA91762.1.
RefSeqiYP_001765884.1. NC_010508.1.

Genome annotation databases

EnsemblBacteriaiACA91762; ACA91762; Bcenmc03_2601.
GeneIDi6124265.
KEGGibcm:Bcenmc03_2601.
PATRICi19092434. VBIBurCen61509_2700.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000958 Genomic DNA. Translation: ACA91762.1 .
RefSeqi YP_001765884.1. NC_010508.1.

3D structure databases

ProteinModelPortali B1JXI7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 406425.Bcenmc03_2601.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACA91762 ; ACA91762 ; Bcenmc03_2601 .
GeneIDi 6124265.
KEGGi bcm:Bcenmc03_2601.
PATRICi 19092434. VBIBurCen61509_2700.

Phylogenomic databases

eggNOGi COG1878.
HOGENOMi HOG000219455.
KOi K07130.
OMAi HTSKWPL.
OrthoDBi EOG67T5JJ.

Enzyme and pathway databases

UniPathwayi UPA00333 ; UER00454 .
BioCyci BCEN406425:GHD9-2673-MONOMER.

Family and domain databases

HAMAPi MF_01969. KynB.
InterProi IPR007325. KFase.
IPR017484. Kynurenine_formamidase_bac.
[Graphical view ]
Pfami PF04199. Cyclase. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR03035. trp_arylform. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 1 of Burkholderia cenocepacia MC0-3."
    Copeland A., Lucas S., Lapidus A., Barry K., Bruce D., Goodwin L., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L.
    , Kyrpides N., Mikhailova N., Tiedje J., Richardson P.
    Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MC0-3.

Entry informationi

Entry nameiKYNB_BURCC
AccessioniPrimary (citable) accession number: B1JXI7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: April 29, 2008
Last modified: November 26, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3