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B1JXI7

- KYNB_BURCC

UniProt

B1JXI7 - KYNB_BURCC

Protein

Kynurenine formamidase

Gene

kynB

Organism
Burkholderia cenocepacia (strain MC0-3)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (29 Apr 2008)
      Previous versions | rss
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    Functioni

    Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.UniRule annotation

    Catalytic activityi

    N-formyl-L-kynurenine + H2O = formate + L-kynurenine.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. arylformamidase activity Source: UniProtKB
    2. formamidase activity Source: InterPro

    GO - Biological processi

    1. anthranilate metabolic process Source: UniProtKB
    2. tryptophan catabolic process to kynurenine Source: UniProtKB

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Tryptophan catabolism

    Enzyme and pathway databases

    BioCyciBCEN406425:GHD9-2673-MONOMER.
    UniPathwayiUPA00333; UER00454.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Kynurenine formamidaseUniRule annotation (EC:3.5.1.9UniRule annotation)
    Short name:
    KFAUniRule annotation
    Short name:
    KFaseUniRule annotation
    Alternative name(s):
    ArylformamidaseUniRule annotation
    N-formylkynurenine formamidaseUniRule annotation
    Short name:
    FKFUniRule annotation
    Gene namesi
    Name:kynBUniRule annotation
    Ordered Locus Names:Bcenmc03_2601
    OrganismiBurkholderia cenocepacia (strain MC0-3)
    Taxonomic identifieri406425 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
    ProteomesiUP000002169: Chromosome 1

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 213213Kynurenine formamidasePRO_0000362101Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi406425.Bcenmc03_2601.

    Structurei

    3D structure databases

    ProteinModelPortaliB1JXI7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the KynB family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1878.
    HOGENOMiHOG000219455.
    KOiK07130.
    OMAiHTSKWPL.
    OrthoDBiEOG67T5JJ.

    Family and domain databases

    HAMAPiMF_01969. KynB.
    InterProiIPR007325. KFase.
    IPR017484. Kynurenine_formamidase_bac.
    [Graphical view]
    PfamiPF04199. Cyclase. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR03035. trp_arylform. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B1JXI7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDTLWDISPP VSPATPVWPG DTPVAVERVW RMEAGSPVNV ARLTLSPHTG    50
    AHCDAPLHYD ADGAPIGAVP LDTYLGPCRV IHCIGASPVV RPADVEVALD 100
    GVPPRVLLRT YARAAVEQWD SAFCAVAPDT VDLLAAHGVK LIGIDTPSLD 150
    PQESKTMDAH HRVRAHRMAI LEGIVLDDVP PGDYELIALP LKFATLDASP 200
    VRAVLRALPA HAS 213
    Length:213
    Mass (Da):22,662
    Last modified:April 29, 2008 - v1
    Checksum:iEDFC1F20167A178B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000958 Genomic DNA. Translation: ACA91762.1.
    RefSeqiWP_012329112.1. NC_010508.1.
    YP_001765884.1. NC_010508.1.

    Genome annotation databases

    EnsemblBacteriaiACA91762; ACA91762; Bcenmc03_2601.
    GeneIDi6124265.
    KEGGibcm:Bcenmc03_2601.
    PATRICi19092434. VBIBurCen61509_2700.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000958 Genomic DNA. Translation: ACA91762.1 .
    RefSeqi WP_012329112.1. NC_010508.1.
    YP_001765884.1. NC_010508.1.

    3D structure databases

    ProteinModelPortali B1JXI7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 406425.Bcenmc03_2601.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACA91762 ; ACA91762 ; Bcenmc03_2601 .
    GeneIDi 6124265.
    KEGGi bcm:Bcenmc03_2601.
    PATRICi 19092434. VBIBurCen61509_2700.

    Phylogenomic databases

    eggNOGi COG1878.
    HOGENOMi HOG000219455.
    KOi K07130.
    OMAi HTSKWPL.
    OrthoDBi EOG67T5JJ.

    Enzyme and pathway databases

    UniPathwayi UPA00333 ; UER00454 .
    BioCyci BCEN406425:GHD9-2673-MONOMER.

    Family and domain databases

    HAMAPi MF_01969. KynB.
    InterProi IPR007325. KFase.
    IPR017484. Kynurenine_formamidase_bac.
    [Graphical view ]
    Pfami PF04199. Cyclase. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR03035. trp_arylform. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome 1 of Burkholderia cenocepacia MC0-3."
      Copeland A., Lucas S., Lapidus A., Barry K., Bruce D., Goodwin L., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L.
      , Kyrpides N., Mikhailova N., Tiedje J., Richardson P.
      Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MC0-3.

    Entry informationi

    Entry nameiKYNB_BURCC
    AccessioniPrimary (citable) accession number: B1JXI7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 10, 2009
    Last sequence update: April 29, 2008
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3