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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Burkholderia cenocepacia (strain MC0-3)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei219 – 2191UniRule annotation
Active sitei661 – 6611UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciBCEN406425:GHD9-2500-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Bcenmc03_2430Imported
OrganismiBurkholderia cenocepacia (strain MC0-3)Imported
Taxonomic identifieri406425 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000002169 Componenti: Chromosome 1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi406425.Bcenmc03_2430.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1JWR1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSSGSARTA RRNAALPSPD ASTDTVATAA NGRAKTAAKP TATKPKDPIR
60 70 80 90 100
QTKRTTKAAS PAARNAVAPK AGTRTRDNKD GPLFEDIRFL GRLLGDVVRE
110 120 130 140 150
QEGDTVFDVV ETIRQTAVKF RREGDSEAAQ TLEKKLRKLT PEQTVSVVRA
160 170 180 190 200
FSYFSHLANI AEDRHHNRRR RIHALAGSAP QPGTVAYALD QLKTTGNASK
210 220 230 240 250
RLLQRFFDDA LIVPVLTAHP TEVQRKSILD AQHDIARLLA ERDQELTARE
260 270 280 290 300
RQYNETMLRA RVTALWQTRM LRDARLTVGD EIENALSYYR ATFLDELPAL
310 320 330 340 350
YGDIEAALAE HGLSARVPAF FQMGSWIGGD RDGNPNVTAA TLDEAINRQA
360 370 380 390 400
AVILEHYLEQ VHKLGAELSV SNLLVGANDA VKALAAASPD QSPHRVDEPY
410 420 430 440 450
RRALIGIYTR LAASARVRLG EGTVPVRSAG RGAPPVRAIP YEDSEAFVAD
460 470 480 490 500
LKVLTASLDE HHGASLAAPR LAPLVRAAEV FGFHLASIDL RQSSDIHEAV
510 520 530 540 550
VAELFARAGV EADYAALAEE DKLRVLLAAL ADPRPLRSPY LEYSALAQSE
560 570 580 590 600
LGVFEKAREV RAQFGARAVR NYIISHTETV SDLVEVLLLQ KETGLLEGTL
610 620 630 640 650
GVPGSHAKNS LMVIPLFETI PDLRDASRIM RDYFALPGID ALIAHQGAEQ
660 670 680 690 700
EVMLGYSDSN KDGGFLTSNW ELYRAELALV DLFRERKITL RLFHGRGGTV
710 720 730 740 750
GRGGGPTYQA ILSQPPGTVN GQIRLTEQGE VIASKFSNPS IGRRNLETVV
760 770 780 790 800
AATLEASLLP QSNAPAQLPA FEAAMQTLSD SAMAAYRALV YETPGFTDYF
810 820 830 840 850
FSSTPITEIA ELNIGSRPAS RKLQDPKQRK IEDLRAIPWG FSWGQCRLLL
860 870 880 890 900
TGWYGFGSAV SAYLDGAQDD AERAKRVTLL KKMNKTWPFF ANLLSNMDMV
910 920 930 940 950
LAKTDLAVAS RYAQLVSDRK LRKHVFERIV AEWERTSRAL AEITGQEGRL
960 970 980 990 1000
ATNPLLARSI KNRFPYLDPL NHLQVELIKR HRAGDTNARL RRGIHLTING

IAAGLRNTG
Length:1,009
Mass (Da):110,805
Last modified:April 28, 2008 - v1
Checksum:i2AB5F1909ADD0788
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000958 Genomic DNA. Translation: ACA91591.1.
RefSeqiWP_012329001.1. NC_010508.1.
YP_001765713.1. NC_010508.1.

Genome annotation databases

EnsemblBacteriaiACA91591; ACA91591; Bcenmc03_2430.
KEGGibcm:Bcenmc03_2430.
PATRICi19092082. VBIBurCen61509_2526.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000958 Genomic DNA. Translation: ACA91591.1.
RefSeqiWP_012329001.1. NC_010508.1.
YP_001765713.1. NC_010508.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi406425.Bcenmc03_2430.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACA91591; ACA91591; Bcenmc03_2430.
KEGGibcm:Bcenmc03_2430.
PATRICi19092082. VBIBurCen61509_2526.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciBCEN406425:GHD9-2500-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome 1 of Burkholderia cenocepacia MC0-3."
    Copeland A., Lucas S., Lapidus A., Barry K., Bruce D., Goodwin L., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L.
    , Kyrpides N., Mikhailova N., Tiedje J., Richardson P.
    Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MC0-3Imported.

Entry informationi

Entry nameiB1JWR1_BURCC
AccessioniPrimary (citable) accession number: B1JWR1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 28, 2008
Last sequence update: April 28, 2008
Last modified: March 31, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.